SCHEMBL28969877

SCHEMBL28969877

NCC(=O)NCCOC(N)=O

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 2/20 0.39
CHRM4 P08173 2/20 0.39
CHRM5 P08912 2/20 0.39
CHRM1 P11229 2/20 0.39
CHRM3 P20309 2/20 0.39
CHRNB2 P17787 2/20 0.39
CHRNA4 P43681 2/20 0.39
LMNA P02545 2/20 0.39
TSHR P16473 2/20 0.39
HTR1A P08908 1/20 0.39
CYP2C19 P33261 1/20 0.39
CHRNA7 P36544 1/20 0.39
CA2 P00918 3/20 0.39
ALOX15 P16050 1/20 0.36
CA1 P00915 2/20 0.35
CHRNB4 P30926 1/20 0.34
CHRNA3 P32297 1/20 0.34
NPC1 O15118 1/20 0.30
USP2 O75604 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL25328852 0.98 CA2 (0.38) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL20472112 0.92 CA2 (0.35) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL9795107 0.84 CA2 (0.40) TSHRCA2CA1NPC1USP2
SCHEMBL31050436 0.84 ALDH1A1 (0.42)
SCHEMBL2249679 0.83 CHRM2 (0.41) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL6037070 0.83 CA2 (0.39) LMNATSHRCA2CA1NPC1
SCHEMBL25282552 0.83 ALDH1A1 (0.48) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL25439321 0.81 CHRM2 (0.38) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL27520156 0.81 FAAH (0.42) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL8496243 0.79 CA2 (0.41) LMNATSHRCYP2C19CA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115835860-A Novel analogues of pterostilbene amino acids with carbonate for the treatment of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis 树顶分子生技股份有限公司 2023-03-21 CN disclosed