Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27788814 | 0.98 | FAAH (0.41) | FAAHMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL14890563 | 0.85 | FAAH (0.43) | FAAHMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL14890445 | 0.83 | FAAH (0.42) | FAAHMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL9795107 | 0.83 | CA2 (0.40) | MEN1KMT2AALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL27360180 | 0.81 | THRB (0.46) | FAAHMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL28969877 | 0.81 | CHRM2 (0.39) | CHRM5CHRM1CHRM3TSHRCHRM2 | |
| SCHEMBL13848563 | 0.81 | MEN1 (0.54) | FAAHMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL6037070 | 0.81 | CA2 (0.39) | SMN1; SMN2TSHRCA2RAB9AKDM4E | |
| Hydrochloric Acid SCHEMBL25328852 | 0.79 | CA2 (0.38) | ALDH1A1CHRM5CHRM1CHRM3TSHR | |
| SCHEMBL11120633 | 0.79 | FAAH (0.42) | FAAHMEN1KMT2ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101328186-A | Thienopyrimidine and thienopyridine derivatives useful as anticancer agents | PFIZER PROD INC (US) | 2008-12-24 | — | — | CN | disclosed |
| CN-1280580-A | Thienopyrimidine and thienopyridine derivatives as anticancer agents | PFIZER PROD INC (US) | 2001-01-17 | — | — | CN | disclosed |