SCHEMBL28969880

SCHEMBL28969880

NCC(=O)NCCNC(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
GLRA1 P23415 1/20 0.38
SLC6A9 P48067 1/20 0.38
OR51E2 Q9H255 1/20 0.38
MMP2 P08253 1/20 0.36
AOC3 Q16853 2/20 0.35
GABRR1 P24046 1/20 0.35
ALDH1A1 P00352 2/20 0.33
CYP2D6 P10635 2/20 0.33
CYP2C19 P33261 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
KDM4E B2RXH2 1/20 0.33
KDM5C P41229 1/20 0.33
PHF8 Q9UPP1 1/20 0.33
KDM2A Q9Y2K7 1/20 0.33
ECE1 P42892 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CYP1A2 P05177 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL25330006 0.97 CA1 (0.38) CA1CA2GLRA1SLC6A9OR51E2
SCHEMBL29173783 0.91 TERT (0.37) CA1CA2GLRA1SLC6A9OR51E2
SCHEMBL27189681 0.91 TERT (0.37) CA1CA2GLRA1SLC6A9OR51E2
SCHEMBL3074874 0.89 CA2 (0.44) CA1CA2GLRA1SLC6A9OR51E2
SCHEMBL9979146 0.88 ALDH1A1 (0.50) AOC3ALDH1A1MEN1KMT2AKDM4E
SCHEMBL18160754 0.81 CA2 (0.40) CA1CA2GLRA1SLC6A9OR51E2
SCHEMBL29398784 0.80 CYP2D6 (0.42) MMP2ALDH1A1CYP2D6CYP2C19KDM4E
SCHEMBL4047411 0.80 CYP2D6 (0.45) ALDH1A1CYP2D6CYP2C19MEN1KMT2A
SCHEMBL19776089 0.79 CA2 (0.39) CA1CA2GLRA1SLC6A9OR51E2
SCHEMBL16853212 0.78 ALDH1A1 (0.55) CA1CA2ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115835860-A Novel analogues of pterostilbene amino acids with carbonate for the treatment of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis 树顶分子生技股份有限公司 2023-03-21 CN disclosed