Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5697477 | 0.91 | NR1H2 (0.39) | PREPESR2MAPTNR1H2ALDH1A1 | |
| SCHEMBL4777248 | 0.88 | GLA (0.36) | PREPALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL17267602 | 0.81 | ESR2 (0.38) | PREPESR2MAPTNR1H2ALDH1A1 | |
| SCHEMBL30910213 | 0.74 | ACHE (0.40) | ALDH1A1LMNAHSD17B10GPR119MEN1 | |
| SCHEMBL3110330 | 0.73 | MAPT (0.36) | PREPESR2MAPTNR1H2ALDH1A1 | |
| SCHEMBL7484898 | 0.71 | GPR119 (0.34) | ESR2MAPTALDH1A1LMNAUSP2 | |
| SCHEMBL13947269 | 0.69 | TP53 (0.36) | MAPTALDH1A1ATMTP53ALOX15 | |
| SCHEMBL30793490 | 0.69 | NR1H2 (0.47) | PREPESR2MAPTNR1H2USP2 | |
| SCHEMBL15414407 | 0.68 | PREP (0.40) | PREPESR2MAPTNR1H2ALDH1A1 | |
| SCHEMBL13947265 | 0.68 | TP53 (0.35) | MAPTALDH1A1TP53ALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115806561-A | JAK3 selective inhibitors and uses thereof | 南京药石科技股份有限公司 | 2023-03-17 | — | — | CN | disclosed |
| CN-114364675-A | CDK inhibitors | 上海齐鲁锐格医药研发有限公司 | 2022-04-15 | — | — | CN | disclosed |