Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5184141 | 0.81 | BCHE (0.47) | BCHENR1H2KMT2AMEN1L3MBTL1 | |
| SCHEMBL29168570 | 0.80 | BCHE (0.35) | BCHEBACE1NR1H2KMT2AMEN1 | |
| SCHEMBL2144869 | 0.73 | USP30 (0.40) | BCHEBACE1NR1H2NPC1RAB9A | |
| SCHEMBL8288797 | 0.72 | BCHE (0.38) | BCHENR1H2KMT2AMEN1HTT | |
| SCHEMBL20572028 | 0.72 | AAK1 (0.38) | BCHEKMT2AMEN1PIK3R1PIK3CA | |
| SCHEMBL17631624 | 0.71 | HDAC8 (0.39) | UCHL1BCHEBACE1NR1H2KMT2A | |
| SCHEMBL1284244 | 0.71 | L3MBTL1 (0.44) | UCHL1BCHENR1H2KMT2AMEN1 | |
| SCHEMBL29496262 | 0.71 | POLB (0.43) | BCHEKMT2AMEN1HTTGPR119 | |
| SCHEMBL29507058 | 0.71 | L3MBTL1 (0.44) | UCHL1BCHENR1H2KMT2AMEN1 | |
| SCHEMBL1314041 | 0.71 | ACLY (0.47) | UCHL1BCHEBACE1NR1H2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115806561-A | JAK3 selective inhibitors and uses thereof | 南京药石科技股份有限公司 | 2023-03-17 | — | — | CN | disclosed |