Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18419034 | 0.77 | JAK1 (0.48) | GPR119HTR6CYP3A4 | |
| SCHEMBL23322330 | 0.76 | MET (0.47) | GPR119CYP3A4 | |
| SCHEMBL10227674 | 0.76 | GPR119 (0.49) | GPR119MEN1KMT2AHTR6CYP3A4 | |
| SCHEMBL12612953 | 0.76 | KIT (0.43) | GPR119KITMEN1KMT2AL3MBTL1 | |
| SCHEMBL21714346 | 0.76 | CCNT1 (0.45) | GPR119KITHTR6CYP3A4 | |
| SCHEMBL25259649 | 0.75 | HTR6 (0.41) | GPR119MEN1KMT2AMKNK1L3MBTL1 | |
| SCHEMBL17583115 | 0.75 | GPR119 (0.60) | GPR119HTR6CYP3A4 | |
| SCHEMBL29838827 | 0.75 | JAK1 (0.58) | GPR119 | |
| SCHEMBL17951172 | 0.75 | GPR119 (0.44) | GPR119MEN1KMT2AHTR6CYP3A4 | |
| SCHEMBL19725938 | 0.74 | NAMPT (0.43) | GPR119MEN1KMT2AHTR6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115806561-A | JAK3 selective inhibitors and uses thereof | 南京药石科技股份有限公司 | 2023-03-17 | — | — | CN | disclosed |