Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28452492 | 0.90 | APLNR (0.63) | APLNRTP53TSHRHTR2AHTR2C | |
| SCHEMBL22537210 | 0.85 | APLNR (0.54) | APLNRTP53TSHRKDM4ECNR1 | |
| SCHEMBL22537209 | 0.85 | APLNR (0.57) | APLNRTP53TSHRCNR1CNR2 | |
| SCHEMBL20530830 | 0.85 | APLNR (0.54) | APLNRTP53TSHRHTR2AHTR2C | |
| SCHEMBL11300017 | 0.85 | TP53 (0.55) | APLNRTP53TSHRHTR2AHTR2C | |
| SCHEMBL12492811 | 0.83 | ALDH1A1 (0.53) | APLNRTP53KDM4EMAPTALDH1A1 | |
| SCHEMBL1530735 | 0.82 | APLNR (0.65) | APLNRTP53TSHRCNR2HTR2A | |
| SCHEMBL12525710 | 0.81 | APLNR (0.49) | APLNRTP53HTR2AHTR2CMAPT | |
| SCHEMBL12493456 | 0.81 | MMP8 (0.50) | APLNRTP53HTR2AHTR2CSMN1; SMN2 | |
| SCHEMBL31326423 | 0.81 | APLNR (0.55) | APLNRTP53TSHRHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115836058-A | Benzisoxazole derivatives | 住友制药株式会社 | 2023-03-21 | — | — | CN | disclosed |