Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 3/20 | 0.47 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 4/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4493764 | 0.82 | RIPK1 (0.50) | RIPK1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL4404016 | 0.79 | RIPK1 (0.46) | RIPK1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL20427979 | 0.77 | RIPK1 (0.45) | RIPK1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL861831 | 0.76 | RIPK1 (0.50) | RIPK1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL4481161 | 0.72 | RIPK1 (0.44) | RIPK1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5252643 | 0.71 | MPO (0.49) | RIPK1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL7700255 | 0.71 | CA3 (0.46) | RIPK1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL19121691 | 0.71 | RIPK1 (0.47) | RIPK1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3870948 | 0.71 | PSEN1 (0.44) | RIPK1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5103997 | 0.69 | TYR (0.46) | RIPK1PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113559802-B | Device and method for synthesizing drug intermediate trifluoromethyl substituted aromatic compound | 北京六合宁远医药科技股份有限公司 | 2023-03-17 | — | — | CN | disclosed |