Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SCARB1 | Q8WTV0 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.38 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.38 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30061980 | 1.00 | LMNA (0.45) | LMNARAB9AKMT2AMEN1NPC1 | |
| SCHEMBL30063129 | 0.82 | NPC1 (0.47) | LMNARAB9AKMT2ANPC1SMN1; SMN2 | |
| SCHEMBL28972120 | 0.82 | NPC1 (0.47) | LMNARAB9AKMT2ANPC1SMN1; SMN2 | |
| SCHEMBL30063043 | 0.80 | RAB9A (0.42) | LMNARAB9AKMT2AMEN1NPC1 | |
| SCHEMBL28972240 | 0.80 | RAB9A (0.42) | LMNARAB9AKMT2AMEN1NPC1 | |
| SCHEMBL28972296 | 0.79 | RAB9A (0.54) | LMNARAB9AKMT2AMEN1NPC1 | |
| SCHEMBL28972486 | 0.79 | SMN1; SMN2 (0.54) | LMNASMN1; SMN2TP53GAAHTT | |
| SCHEMBL30218931 | 0.79 | SMN1; SMN2 (0.54) | LMNASMN1; SMN2TP53GAAHTT | |
| SCHEMBL28972489 | 0.75 | RAB9A (0.49) | LMNARAB9AKMT2AMEN1NPC1 | |
| SCHEMBL28972163 | 0.70 | LMNA (0.48) | LMNARAB9AKMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115667224-A | SCL15A4 small molecule inhibitors with anti-inflammatory activity | 斯克里普斯研究学院 | 2023-01-31 | — | — | CN | disclosed |