Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | EIF4E | P06730 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28972539 | 0.91 | CASP1 (0.42) | MAPTSLC22A12CASP1APPKDM4E | |
| SCHEMBL28972536 | 0.85 | CYP11B2 (0.44) | MAPTSLC22A12APPCYP11B2 | |
| SCHEMBL28972462 | 0.83 | RXRA (0.49) | MAPTAR | |
| SCHEMBL28972700 | 0.81 | EIF4E (0.42) | SLC22A12CASP1EIF4ECYP11B2AR | |
| SCHEMBL30112143 | 0.80 | MAPT (0.47) | MAPTSLC22A12CASP1APPKDM4E | |
| SCHEMBL28972449 | 0.76 | CYP11B2 (0.43) | MAPTSLC22A12APPCYP11B2 | |
| SCHEMBL28972688 | 0.76 | EGLN2 (0.39) | MAPTSLC22A12EIF4ECYP11B2AR | |
| SCHEMBL30112089 | 0.75 | MAPT (0.45) | MAPTAPPKDM4EARTBXAS1 | |
| SCHEMBL28972519 | 0.75 | MAPT (0.45) | MAPTAPPKDM4EARTBXAS1 | |
| SCHEMBL28972461 | 0.74 | AR (0.45) | APPAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110016011-B | Amide derivative and medical use thereof | 北京美倍他药物研究有限公司 | 2023-02-03 | — | — | CN | disclosed |