Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4E | P06730 | 3/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 3/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28972450 | 0.90 | CASP1 (0.43) | EIF4EABL1CASP1CYP11B2SLC22A12 | |
| SCHEMBL28972699 | 0.85 | CYP11B2 (0.48) | CYP11B2SLC22A12CYP11B1 | |
| SCHEMBL28972684 | 0.82 | RXRA (0.52) | AR | |
| SCHEMBL28972437 | 0.81 | MAPT (0.41) | EIF4ECASP1CYP11B2SLC22A12NR3C2 | |
| SCHEMBL28972415 | 0.80 | MMP3 (0.39) | — | |
| SCHEMBL30112097 | 0.80 | CYP11B2 (0.46) | EIF4EABL1CASP1CYP11B2SLC22A12 | |
| SCHEMBL28972451 | 0.77 | RORC (0.46) | EIF4ECYP11B2SLC22A12CYP11B1AR | |
| SCHEMBL28972703 | 0.76 | CYP11B2 (0.46) | CYP11B2CYP11B1 | |
| SCHEMBL379474 | 0.75 | AKR1C3 (0.50) | — | |
| SCHEMBL379475 | 0.75 | AKR1C3 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110016011-B | Amide derivative and medical use thereof | 北京美倍他药物研究有限公司 | 2023-02-03 | — | — | CN | disclosed |