Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | TP53 | P04637 | 7/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30218931 | 1.00 | SMN1; SMN2 (0.54) | SMN1; SMN2LMNAL3MBTL1ALDH1A1MAPT | |
| SCHEMBL30063129 | 0.91 | NPC1 (0.47) | SMN1; SMN2LMNAL3MBTL1ALDH1A1MAPT | |
| SCHEMBL28972120 | 0.91 | NPC1 (0.47) | SMN1; SMN2LMNAL3MBTL1ALDH1A1MAPT | |
| SCHEMBL28972264 | 0.81 | ALDH1A1 (0.65) | SMN1; SMN2LMNAL3MBTL1ALDH1A1MAPT | |
| SCHEMBL30218935 | 0.81 | ALDH1A1 (0.65) | SMN1; SMN2LMNAL3MBTL1ALDH1A1MAPT | |
| SCHEMBL28972152 | 0.81 | MAPT (0.51) | SMN1; SMN2LMNAL3MBTL1ALDH1A1MAPT | |
| SCHEMBL30063921 | 0.81 | MAPT (0.51) | SMN1; SMN2LMNAL3MBTL1ALDH1A1MAPT | |
| SCHEMBL28972487 | 0.79 | LMNA (0.45) | SMN1; SMN2LMNAL3MBTL1ALDH1A1MAPT | |
| SCHEMBL30061980 | 0.79 | LMNA (0.45) | SMN1; SMN2LMNAL3MBTL1ALDH1A1MAPT | |
| SCHEMBL27898285 | 0.73 | ALDH1A1 (0.83) | SMN1; SMN2LMNAL3MBTL1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115667224-A | SCL15A4 small molecule inhibitors with anti-inflammatory activity | 斯克里普斯研究学院 | 2023-01-31 | — | — | CN | disclosed |