Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL477635 | 1.00 | LMNA (0.44) | LMNATYREPHX1SMN1; SMN2RIPK1 | |
| SCHEMBL477443 | 1.00 | LMNA (0.44) | LMNATYREPHX1SMN1; SMN2RIPK1 | |
| SCHEMBL26326672 | 0.94 | CA12 (0.50) | EPHX1CA12CA1CA2CA9 | |
| SCHEMBL10708786 | 0.91 | LMNA (0.52) | LMNATYRTDP1 | |
| SCHEMBL3586191 | 0.91 | LMNA (0.52) | LMNATYRTDP1 | |
| SCHEMBL11642416 | 0.90 | CA12 (0.46) | CA12CA1CA2CA9CA14 | |
| SCHEMBL7110307 | 0.83 | CYP3A4 (0.45) | LMNASMN1; SMN2RIPK1L3MBTL1BCHE | |
| SCHEMBL16487204 | 0.82 | SLC6A2 (0.44) | LMNATYREPHX1L3MBTL1MAPT | |
| SCHEMBL18623182 | 0.81 | CA1 (0.51) | LMNATYREPHX1MAPTTDP1 | |
| SCHEMBL8671295 | 0.81 | SMN1; SMN2 (0.58) | LMNASMN1; SMN2L3MBTL1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114014869-B | Chiral 2,2' -bipyridine ligand and preparation method and application thereof | 西安交通大学 | 2023-03-24 | — | — | CN | disclosed |
| CN-114014869-A | Chiral 2,2' -bipyridine ligand and preparation method and application thereof | 西安交通大学 | 2022-02-08 | — | — | CN | disclosed |