SCHEMBL3586191

SCHEMBL3586191

CC(C)(C)c1ccc(C(O)c2ccc(C(C)(C)C)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.52
TYR P14679 1/20 0.52
TSHR P16473 2/20 0.48
ELANE P08246 1/20 0.45
ALDH1A1 P00352 3/20 0.44
HSD17B10 Q99714 2/20 0.44
NR1H4 Q96RI1 2/20 0.42
HDAC1 Q13547 1/20 0.41
SLC22A2 O15244 1/20 0.41
SLC22A1 O15245 1/20 0.41
SLC22A3 O75751 1/20 0.41
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
GRIA4 P48058 2/20 0.40
SRD5A2 P31213 1/20 0.40
GRIN2D O15399 2/20 0.39
GRIN3B O60391 2/20 0.39
GRIN1 Q05586 2/20 0.39
GRIN2A Q12879 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10708786 1.00 LMNA (0.52) LMNATYRTSHRELANEALDH1A1
SCHEMBL477443 0.91 LMNA (0.44) LMNATYRTDP1
SCHEMBL477635 0.91 LMNA (0.44) LMNATYRTDP1
SCHEMBL28973554 0.91 LMNA (0.44) LMNATYRTDP1
SCHEMBL11642416 0.85 CA12 (0.46) KIF11FFAR1
SCHEMBL3692155 0.84 LMNA (0.52) LMNATYRTSHRALDH1A1HSD17B10
SCHEMBL20752299 0.84 LMNA (0.52) LMNATYRTSHRALDH1A1HSD17B10
SCHEMBL18282984 0.82 LMNA (0.50) LMNATYRTSHRALDH1A1HSD17B10
SCHEMBL2644008 0.82 LMNA (0.50) LMNATYRTSHRALDH1A1HSD17B10
SCHEMBL30010731 0.82 LMNA (0.50) LMNATYRTSHRALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0136381-B1 POLYOLEFIN COMPOSITIONS MILLIKEN RESEARCH CORPORATION (US) 1988-06-08 EP claimed
US-4431497-A CARBO ALCOHOLS, ETHERS AND ESTERS AS STABILIZERS; STERILIZATION OF FOOD AND MEDICAL EQUIPMENT PACKAGES; DISCOLORATION INHIBITION MILLIKEN RESEARCH CORPORATION (US) 1984-02-14 US claimed
CN-119823190-A Preparation method of diimine nickel catalyst containing rigid trityl group and application of diimine nickel catalyst in olefin polymerization 安徽大学 2025-04-15 CN disclosed
CN-118530272-A Heteroatom-containing non-metallocene complex and preparation method and application thereof 联泓惠生(江苏)新材料有限公司 2024-08-23 CN disclosed
US-20220287919-A1 PHOTOCURABLE COMPOSITION EXCELLENT IN CURING DEPTH SHOFU INC. (JP) 2022-09-15 US disclosed
US-10025187-B2 Photosensitization chemical-amplification type resist material, method for forming pattern using same, semiconductor device, mask for lithography, and template for nanoimprinting TOKYO ELECTRON LIMITED (JP) 2018-07-17 US disclosed
US-10025187-B2 Photosensitization chemical-amplification type resist material, method for forming pattern using same, semiconductor device, mask for lithography, and template for nanoimprinting TOKYO ELECTRON LIMITED (JP) 2018-07-17 US disclosed
US-10018911-B2 Chemically amplified resist material and resist pattern-forming method JSR CORPORATION (JP) 2018-07-10 US disclosed
US-9971247-B2 Pattern-forming method OSAKA UNIVERSITY (JP) 2018-05-15 US disclosed
US-9971247-B2 Pattern-forming method OSAKA UNIVERSITY (JP) 2018-05-15 US disclosed
US-20170131633-A1 CHEMICALLY AMPLIFIED RESIST MATERIAL AND RESIST PATTERN-FORMING METHOD JSR CORPORATION (JP) 2017-05-11 US disclosed
EP-1706205-B1 A CATALYTICAL ASYMMETRIC EPOXIDATION UNIV CHICAGO (US) 2008-10-29 EP disclosed
US-20070203347-A1 Catalytic asymmetric epoxidation THE UNIVERSITY OF CHICAGO (US) 2007-08-30 US disclosed
US-20070203347-A1 Catalytic asymmetric epoxidation THE UNIVERSITY OF CHICAGO (US) 2007-08-30 US disclosed
US-20070203347-A1 Catalytic asymmetric epoxidation THE UNIVERSITY OF CHICAGO (US) 2007-08-30 US disclosed
US-7202371-B2 Catalytic asymmetric epoxidation THE UNIVERSITY OF CHICAGO (US) 2007-04-10 US disclosed
US-7202371-B2 Catalytic asymmetric epoxidation THE UNIVERSITY OF CHICAGO (US) 2007-04-10 US disclosed
US-7202371-B2 Catalytic asymmetric epoxidation THE UNIVERSITY OF CHICAGO (US) 2007-04-10 US disclosed
US-20050159607-A1 Catalytic asymmetric epoxidation JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2005-07-21 US disclosed
US-4431497-A CARBO ALCOHOLS, ETHERS AND ESTERS AS STABILIZERS; STERILIZATION OF FOOD AND MEDICAL EQUIPMENT PACKAGES; DISCOLORATION INHIBITION MILLIKEN RESEARCH CORPORATION (US) 1984-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10025187-B2 Photosensitization chemical-amplification type resist material, method for forming pattern using same, semiconductor device, mask for lithography, and template for nanoimprinting ASIC1, ASIC3, CLTA LMNA 293/4885TYR 2070/4885TSHR 4284/4885
US-20070203347-A1 Catalytic asymmetric epoxidation DUOX1, DUOX2, EPHX2 LMNA 4683/4885TYR 2315/4885TSHR 3517/4885
US-20220287919-A1 PHOTOCURABLE COMPOSITION EXCELLENT IN CURING DEPTH ODC1, AOC2, CCNT1 LMNA 896/4885TYR 44/4885TSHR 4012/4885
US-10018911-B2 Chemically amplified resist material and resist pattern-forming method SLC11A2, XRCC5, RAD54L LMNA 1379/4885TYR 4614/4885TSHR 2793/4885
US-20050159607-A1 Catalytic asymmetric epoxidation DUOX1, DUOX2, EPHX2 LMNA 4683/4885TYR 2315/4885TSHR 3517/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.