SCHEMBL7110307

SCHEMBL7110307

CC(C)(C)c1cc(C(O)c2ccccc2)cc(C(C)(C)C)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.45
CYP1A2 P05177 1/20 0.45
CYP2C9 P11712 1/20 0.45
TSHR P16473 1/20 0.45
CYP2C19 P33261 1/20 0.45
CNR2 P34972 1/20 0.41
GABRA1 P14867 1/20 0.41
GABRB2 P47870 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
RIPK1 Q13546 1/20 0.40
SLC6A4 P31645 2/20 0.39
AOC3 Q16853 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
CYP2D6 P10635 1/20 0.39
SLC6A2 P23975 1/20 0.39
SLC6A3 Q01959 1/20 0.39
KCNH2 Q12809 1/20 0.39
RXRA P19793 2/20 0.39
RXRB P28702 2/20 0.39
RXRG P48443 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL477443 0.83 LMNA (0.44) SMN1; SMN2RIPK1SLC6A4AOC3L3MBTL1
SCHEMBL28973554 0.83 LMNA (0.44) SMN1; SMN2RIPK1SLC6A4AOC3L3MBTL1
SCHEMBL477635 0.83 LMNA (0.44) SMN1; SMN2RIPK1SLC6A4AOC3L3MBTL1
SCHEMBL14033674 0.80 IDO1 (0.54) TACR1
SCHEMBL26326672 0.78 CA12 (0.50)
SCHEMBL23357364 0.78 GABRA1 (0.42) CYP3A4CYP1A2CYP2C9TSHRCYP2C19
SCHEMBL9778009 0.78 SMN1; SMN2 (0.54) TSHRCNR2SMN1; SMN2L3MBTL1LMNA
SCHEMBL9136246 0.77 TSHR (0.50) CYP3A4CYP1A2CYP2C9TSHRCYP2C19
SCHEMBL30709713 0.77 TSHR (0.50) CYP3A4CYP1A2CYP2C9TSHRCYP2C19
SCHEMBL28647604 0.76 CYP3A4 (0.41) CYP3A4CYP1A2CYP2C9TSHRCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113549062-B Chiral quaternary ammonium salt phase transfer catalyst with high steric hindrance derived from cinchona alkaloid and synthesis method thereof 南京工业大学 2022-08-09 CN claimed
CN-115023460-B Microporous membrane and method for producing same 旭化成株式会社 2024-04-05 CN disclosed
CN-117120528-A Resin pellet composition, method for producing same, and method for producing microporous membrane 旭化成株式会社 2023-11-24 CN disclosed
CN-116710507-A Resin raw material composition for molding, resin raw material composition for microporous film, and method for producing same 旭化成株式会社 2023-09-05 CN disclosed
US-20230271988-A1 METHOD FOR PRODUCING ORGANOMETALLIC NUCLEOPHILE AND REACTION METHOD USING ORGANOMETALLIC NUCLEOPHILE NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) 2023-08-31 US disclosed
CN-115023460-A Microporous membrane and method for producing same 旭化成株式会社 2022-09-06 CN disclosed
CN-113549062-B Chiral quaternary ammonium salt phase transfer catalyst with high steric hindrance derived from cinchona alkaloid and synthesis method thereof 南京工业大学 2022-08-09 CN disclosed
CN-113549062-A Chiral quaternary ammonium salt phase transfer catalyst with high steric hindrance derived from cinchona alkaloid and synthesis method thereof 南京工业大学 2021-10-26 CN disclosed
WO-2021153792-A1 MICROPOROUS FILM, AND METHOD FOR PRODUCING SAME 旭化成株式会社 2021-08-05 WO disclosed
CN-105189649-B Polylactic acid resin composition SK化学公司 2020-08-04 CN disclosed
EP-1354023-A2 LUBRICATING OIL COMPOSITION SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 2003-10-22 EP disclosed
WO-2002053687-A2 LUBRICATING OIL COMPOSITION SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2002-07-11 WO disclosed
CN-1144236-A Flame retardant insulation compositions having enhanced curability QUANTUM CHEM CORP (US) 1997-03-05 CN disclosed
EP-0149191-A2 Low modulus structural foam GENERAL ELECTRIC COMPANY (US) 1985-07-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230271988-A1 METHOD FOR PRODUCING ORGANOMETALLIC NUCLEOPHILE AND REACTION METHOD USING ORGANOMETALLIC NUCLEOPHILE HPD, TALDO1, OGG1 CYP3A4 117/4885CYP1A2 537/4885CYP2C9 241/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.