SCHEMBL10708786

SCHEMBL10708786

CC(C)(C)c1ccc(C(O)c2ccc(C(O)c3ccc(C(C)(C)C)cc3)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.52
TYR P14679 1/20 0.52
TSHR P16473 2/20 0.48
ELANE P08246 1/20 0.45
ALDH1A1 P00352 3/20 0.44
HSD17B10 Q99714 2/20 0.44
NR1H4 Q96RI1 2/20 0.42
HDAC1 Q13547 1/20 0.41
SLC22A2 O15244 1/20 0.41
SLC22A1 O15245 1/20 0.41
SLC22A3 O75751 1/20 0.41
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
GRIA4 P48058 2/20 0.40
SRD5A2 P31213 1/20 0.40
GRIN2D O15399 2/20 0.39
GRIN3B O60391 2/20 0.39
GRIN1 Q05586 2/20 0.39
GRIN2A Q12879 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3586191 1.00 LMNA (0.52) LMNATYRTSHRELANEALDH1A1
SCHEMBL477443 0.91 LMNA (0.44) LMNATYRTDP1
SCHEMBL477635 0.91 LMNA (0.44) LMNATYRTDP1
SCHEMBL28973554 0.91 LMNA (0.44) LMNATYRTDP1
SCHEMBL11642416 0.85 CA12 (0.46) KIF11FFAR1
SCHEMBL3692155 0.84 LMNA (0.52) LMNATYRTSHRALDH1A1HSD17B10
SCHEMBL20752299 0.84 LMNA (0.52) LMNATYRTSHRALDH1A1HSD17B10
SCHEMBL18282984 0.82 LMNA (0.50) LMNATYRTSHRALDH1A1HSD17B10
SCHEMBL2644008 0.82 LMNA (0.50) LMNATYRTSHRALDH1A1HSD17B10
SCHEMBL30010731 0.82 LMNA (0.50) LMNATYRTSHRALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0136381-B1 POLYOLEFIN COMPOSITIONS MILLIKEN RESEARCH CORPORATION (US) 1988-06-08 EP claimed
EP-0136381-A1 Polyolefin compositions MILLIKEN RESEARCH CORPORATION (US) 1985-04-10 EP claimed
EP-0136381-B1 POLYOLEFIN COMPOSITIONS MILLIKEN RESEARCH CORPORATION (US) 1988-06-08 EP disclosed
EP-0136381-A1 Polyolefin compositions MILLIKEN RESEARCH CORPORATION (US) 1985-04-10 EP disclosed
US-4431497-A CARBO ALCOHOLS, ETHERS AND ESTERS AS STABILIZERS; STERILIZATION OF FOOD AND MEDICAL EQUIPMENT PACKAGES; DISCOLORATION INHIBITION MILLIKEN RESEARCH CORPORATION (US) 1984-02-14 US disclosed