Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 5/20 | 0.42 |
| ▸ | F11 | P03951 | 7/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30680273 | 0.86 | MMP1 (0.44) | PDE4AF11MEN1KMT2A | |
| SCHEMBL28974403 | 0.86 | MMP1 (0.44) | PDE4AF11MEN1KMT2A | |
| SCHEMBL23486816 | 0.86 | MMP1 (0.44) | PDE4AF11MEN1KMT2A | |
| SCHEMBL28974423 | 0.79 | GRIK1 (0.43) | F11ADRB2ADRB1ADRB3 | |
| SCHEMBL23486883 | 0.79 | CAPN1 (0.45) | PDE4APDE4BPDE4CPDE4DMEN1 | |
| SCHEMBL28974391 | 0.78 | IRAK4 (0.41) | F11SMN1; SMN2ALDH1A1LTA4HIRAK4 | |
| SCHEMBL23486820 | 0.78 | MMP1 (0.42) | F11MEN1KMT2ANPSR1 | |
| SCHEMBL23486821 | 0.78 | MMP1 (0.42) | F11MEN1KMT2ANPSR1 | |
| SCHEMBL28974365 | 0.78 | CTSD (0.42) | F11ADRB3 | |
| SCHEMBL28974592 | 0.77 | F11 (0.41) | F11SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728917-A | Oxamide derivative, preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2022-07-08 | — | — | CN | disclosed |