Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | F11 | P03951 | 9/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30680273 | 1.00 | MMP1 (0.44) | MMP1KLKB1PLGPLAUF11 | |
| SCHEMBL23486816 | 1.00 | MMP1 (0.44) | MMP1KLKB1PLGPLAUF11 | |
| SCHEMBL23486820 | 0.90 | MMP1 (0.42) | MMP1KLKB1PLGPLAUF11 | |
| SCHEMBL23486821 | 0.90 | MMP1 (0.42) | MMP1KLKB1PLGPLAUF11 | |
| SCHEMBL30680348 | 0.87 | CMA1 (0.40) | MMP1MEN1KMT2A | |
| SCHEMBL23486351 | 0.87 | KLKB1 (0.47) | MMP1KLKB1PLGPLAUF11 | |
| SCHEMBL28974402 | 0.86 | PDE4A (0.42) | F11PDE4AMEN1KMT2A | |
| SCHEMBL29139606 | 0.85 | S1PR1 (0.44) | KLKB1F11S1PR1CYP2D6 | |
| SCHEMBL23466497 | 0.84 | F11 (0.46) | F11S1PR1CYP2D6 | |
| SCHEMBL23466496 | 0.84 | F11 (0.46) | F11S1PR1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728917-B | Oxamide derivative, preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-114728917-A | Oxamide derivative, preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2022-07-08 | — | — | CN | disclosed |