SCHEMBL2897487

SCHEMBL2897487

COc1cc(OC)nc(Sc2cc[c]cn2)n1

nearest known ligand 0.40

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.33
LMNA P02545 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2900170 0.84
SCHEMBL2900607 0.79 POLB (0.41) LMNASMN1; SMN2ALDH1A1
SCHEMBL2902661 0.78 L3MBTL1 (0.31) L3MBTL1
SCHEMBL2894750 0.77 L3MBTL1 (0.37) L3MBTL1LMNASMN1; SMN2ALDH1A1
SCHEMBL2902762 0.76
SCHEMBL2900809 0.74 L3MBTL1 (0.50) L3MBTL1LMNASMN1; SMN2ALDH1A1
SCHEMBL37909 0.73
SCHEMBL2903350 0.71 HAO1 (0.47) SMN1; SMN2ALDH1A1
SCHEMBL1037031 0.71 SMN1; SMN2 (0.37) L3MBTL1SMN1; SMN2ALDH1A1
SCHEMBL2903124 0.70 ALDH1A1 (0.49) SMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100305124-A1 Acylated Aminopyridine and Aminopyridazine Insecticides BAYER CROPSCIENCE AG (DE) 2010-12-02 US disclosed
EP-2236505-A1 Acylated aminopyridines and pyridazines as insecticides Bayer CropScience AG (DE) 2010-10-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100305124-A1 Acylated Aminopyridine and Aminopyridazine Insecticides AAAS, DDT, QDPR L3MBTL1 1263/4885LMNA 2262/4885SMN1; SMN2 2519/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.