SCHEMBL2903350

SCHEMBL2903350

COc1ccc(Sc2cc[c]cn2)cc1

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HAO1 Q9UJM8 1/20 0.47
PTGIR P43119 8/20 0.39
CDC7 O00311 1/20 0.38
DBF4 Q9UBU7 1/20 0.38
MAPT P10636 4/20 0.38
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
POLB P06746 1/20 0.37
ALDH1A1 P00352 1/20 0.37
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA7 P43166 1/20 0.37
CA9 Q16790 1/20 0.37
CA14 Q9ULX7 1/20 0.37
FBP1 P09467 1/20 0.36
NPSR1 Q6W5P4 1/20 0.35
RXFP1 Q9HBX9 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2903109 0.81 SMN1; SMN2 (0.44) HAO1PTGIRMAPTMEN1KMT2A
SCHEMBL2897559 0.79 L3MBTL1 (0.50) HAO1PTGIRMAPTMEN1KMT2A
SCHEMBL1034623 0.77 HPGD (0.43) MAPTMEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL920051 0.76 PTGIR (0.52) HAO1PTGIRMEN1KMT2APOLB
SCHEMBL7954383 0.75 DDAH1 (0.48) MAPTMEN1KMT2A
SCHEMBL2903058 0.74 MEN1 (0.44) HAO1MAPTMEN1KMT2APOLB
SCHEMBL2895353 0.73 HAO1 (0.47) HAO1PTGIRMAPTMEN1KMT2A
SCHEMBL2900170 0.73
SCHEMBL9018844 0.72 L3MBTL1 (0.61) HAO1MAPTMEN1KMT2ASMN1; SMN2
Hydrochloric Acid SCHEMBL7273479 0.71 L3MBTL1 (0.64) HAO1MAPTMEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100305124-A1 Acylated Aminopyridine and Aminopyridazine Insecticides BAYER CROPSCIENCE AG (DE) 2010-12-02 US disclosed
EP-2236505-A1 Acylated aminopyridines and pyridazines as insecticides Bayer CropScience AG (DE) 2010-10-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100305124-A1 Acylated Aminopyridine and Aminopyridazine Insecticides AAAS, DDT, QDPR HAO1 3072/4885PTGIR 1677/4885CDC7 3922/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.