SCHEMBL28975481

SCHEMBL28975481

Nc1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=S)[nH]c1=O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PYGM P11217 3/20 0.57
SLC28A1 O00337 1/20 0.51
SLC28A2 O43868 1/20 0.51
SLC29A1 Q99808 1/20 0.51
SLC28A3 Q9HAS3 1/20 0.51
TK2 O00142 2/20 0.50
P2RY2 P41231 1/20 0.49
LMNA P02545 2/20 0.49
MTOR P42345 2/20 0.49
TP53 P04637 2/20 0.49
THRB P10828 1/20 0.49
MDM2 Q00987 1/20 0.49
NCOA1 Q15788 1/20 0.49
NCOA3 Q9Y6Q9 1/20 0.49
GMNN O75496 1/20 0.49
ALDH1A1 P00352 1/20 0.49
NFKB1 P19838 1/20 0.49
DNMT1 P26358 1/20 0.49
THPO P40225 1/20 0.49
HTT P42858 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6671812 0.87 PYGM (0.70) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL1138789 0.87 PYGM (0.70) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL1138786 0.87 PYGM (0.70) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL26369667 0.85 PYGM (0.55) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL1965358 0.85 PYGM (0.55) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL18503571 0.85 PYGM (0.55) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL18512964 0.85 PYGM (0.55) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL1965361 0.85 PYGM (0.55) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL18512965 0.85 PYGM (0.55) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL11883660 0.85 PYGM (0.57) PYGMSLC28A1SLC28A2SLC29A1SLC28A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115701285-A Mesenchymal stem cell therapy 菲克特生物科学股份有限公司 2023-02-07 CN disclosed