SCHEMBL6671812

SCHEMBL6671812

Nc1cn(C2OC(CO)C(O)C2O)c(=O)[nH]c1=O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PYGM P11217 3/20 0.70
TK2 O00142 2/20 0.65
SLC28A1 O00337 1/20 0.60
SLC28A2 O43868 1/20 0.60
SLC29A1 Q99808 1/20 0.60
SLC28A3 Q9HAS3 1/20 0.60
P2RY2 P41231 2/20 0.54
DNPH1 O43598 1/20 0.52
LMNA P02545 2/20 0.51
MTOR P42345 2/20 0.51
THRB P10828 1/20 0.51
MDM2 Q00987 1/20 0.51
NCOA1 Q15788 1/20 0.51
NCOA3 Q9Y6Q9 1/20 0.51
GMNN O75496 1/20 0.51
ALDH1A1 P00352 1/20 0.51
TP53 P04637 1/20 0.51
NFKB1 P19838 1/20 0.51
DNMT1 P26358 1/20 0.51
THPO P40225 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1138786 1.00 PYGM (0.70) PYGMTK2SLC28A1SLC28A2SLC29A1
SCHEMBL1138789 1.00 PYGM (0.70) PYGMTK2SLC28A1SLC28A2SLC29A1
Phosphoric Acid SCHEMBL6519313 0.95 PYGM (0.65) PYGMTK2SLC28A1SLC28A2SLC29A1
SCHEMBL2583461 0.88 PYGM (0.56) PYGMTK2SLC28A1SLC28A2SLC29A1
SCHEMBL15011448 0.87 P2RY2 (0.63) PYGMTK2SLC28A1SLC28A2SLC29A1
SCHEMBL28975480 0.87 P2RY2 (0.63) PYGMTK2SLC28A1SLC28A2SLC29A1
SCHEMBL28975481 0.87 PYGM (0.57) PYGMTK2SLC28A1SLC28A2SLC29A1
SCHEMBL2056641 0.85 PYGM (0.72) PYGMTK2SLC28A1SLC28A2SLC29A1
SCHEMBL14928850 0.85 PYGM (0.72) PYGMTK2SLC28A1SLC28A2SLC29A1
SCHEMBL2056643 0.85 PYGM (0.72) PYGMTK2SLC28A1SLC28A2SLC29A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004037159-A2 COMPOUNDS, COMPOSITIONS AND METHODS FOR MODULATING FAT METABOLISM OBETHERAPY BIOTECHNOLOGY (FR) 2004-05-06 WO disclosed