SCHEMBL1138786

SCHEMBL1138786

Nc1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)[nH]c1=O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PYGM P11217 3/20 0.70
TK2 O00142 2/20 0.65
SLC28A1 O00337 1/20 0.60
SLC28A2 O43868 1/20 0.60
SLC29A1 Q99808 1/20 0.60
SLC28A3 Q9HAS3 1/20 0.60
P2RY2 P41231 2/20 0.54
DNPH1 O43598 1/20 0.52
LMNA P02545 2/20 0.51
MTOR P42345 2/20 0.51
THRB P10828 1/20 0.51
MDM2 Q00987 1/20 0.51
NCOA1 Q15788 1/20 0.51
NCOA3 Q9Y6Q9 1/20 0.51
GMNN O75496 1/20 0.51
ALDH1A1 P00352 1/20 0.51
TP53 P04637 1/20 0.51
NFKB1 P19838 1/20 0.51
DNMT1 P26358 1/20 0.51
THPO P40225 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6671812 1.00 PYGM (0.70) PYGMTK2SLC28A1SLC28A2SLC29A1
SCHEMBL1138789 1.00 PYGM (0.70) PYGMTK2SLC28A1SLC28A2SLC29A1
Phosphoric Acid SCHEMBL6519313 0.95 PYGM (0.65) PYGMTK2SLC28A1SLC28A2SLC29A1
SCHEMBL2583461 0.88 PYGM (0.56) PYGMTK2SLC28A1SLC28A2SLC29A1
SCHEMBL15011448 0.87 P2RY2 (0.63) PYGMTK2SLC28A1SLC28A2SLC29A1
SCHEMBL28975480 0.87 P2RY2 (0.63) PYGMTK2SLC28A1SLC28A2SLC29A1
SCHEMBL28975481 0.87 PYGM (0.57) PYGMTK2SLC28A1SLC28A2SLC29A1
SCHEMBL2056641 0.85 PYGM (0.72) PYGMTK2SLC28A1SLC28A2SLC29A1
SCHEMBL14928850 0.85 PYGM (0.72) PYGMTK2SLC28A1SLC28A2SLC29A1
SCHEMBL2056643 0.85 PYGM (0.72) PYGMTK2SLC28A1SLC28A2SLC29A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 399 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144879-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS AI-BIOPHARMA (FR) 2026-05-28 US claimed
US-20260049338-A1 METHODS AND PRODUCTS FOR TRANSFECTING CELLS FACTOR BIOSCIENCE INC (US) 2026-02-19 US claimed
US-12384740-B2 Cationic lipids and transfection methods FACTOR BIOSCIENCE INC. (US) 2025-08-12 US claimed
US-12357664-B2 Optimized oncolytic viruses and uses thereof SATOR THERAPEUTICS (US) 2025-07-15 US claimed
CN-114450265-B Cationic lipids and uses thereof 菲克特生物科学股份有限公司 2024-12-24 CN claimed
US-20240139325-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS AI-BIOPHARMA (FR) 2024-05-02 US claimed
US-20230373903-A1 CATIONIC LIPIDS AND TRANSFECTION METHODS FACTOR BIOSCIENCE INC. 2023-11-23 US claimed
US-11814333-B2 Cationic lipids and transfection methods FACTOR BIOSCIENCE INC. (US) 2023-11-14 US claimed
US-20230323399-A1 METHODS AND PRODUCTS FOR TRANSFECTING CELLS FACTOR BIOSCIENCE INC. 2023-10-12 US claimed
US-20230304044-A1 METHODS AND PRODUCTS FOR TRANSFECTING CELLS FACTOR BIOSCIENCE INC. 2023-09-28 US claimed
US-20020004590-A1 Method for producing nucleoside-5'-phosphate ester MIHARA YASUHIRO (JP) 2002-01-10 US claimed
US-6207435-B1 MUTANT ACID PHOSPHATASE HAVING DECREASED MICHAELIS CONSTANT FOR A NUCLEOSIDE AND/OR INCREASED TEMPERATURE STABILITY; FOR EFFICIENT PHOSPHORYLATION OF NUCLEOSIDES TO PRODUCE NUCLEOTIDES AJINOMOTO CO., INC. (JP) 2001-03-27 US claimed
EP-0661291-B1 Solid phase synthesis of oligoribonucleotide AVENTIS PHARMA GMBH (DE) 2001-03-07 EP claimed
US-6063628-A Induction of viral mutation by incorporation of miscoding ribonucleoside analogs into viral RNA UNIVERSITY OF WASHINGTON (US) 2000-05-16 US claimed
US-6015697-A ECONOMICAL AND EFFICIENT PROCESS BY REACTING A NUCLEOSIDE WITH A PHOSPHATE DONOR GROUP IN PRESENCE OF MUTANT ACID PHOSPHATASE WITH DECREASED MICHAELIS CONSTANT FOR NUCLEOSIDE OR INCREASED TEMPERATURE STABILITY AJINOMOTO CO., INC. (JP) 2000-01-18 US claimed
EP-0948256-A1 INDUCTION OF VIRAL MUTATION BY INCORPORATION OF MISCODING RIBONUCLEOSIDE ANALOGS INTO VIRAL RNA THE UNIVERSITY OF WASHINGTON (US) 1999-10-13 EP claimed
WO-1998018324-A1 INDUCTION OF VIRAL MUTATION BY INCORPORATION OF MISCODING RIBONUCLEOSIDE ANALOGS INTO VIRAL RNA THE UNIVERSITY OF WASHINGTON (US) 1998-05-07 WO claimed
US-5652358-A Solid-phase synthesis of oligoribonucleotides HOECHST AKTIENGESELLSCHAFT (DE) 1997-07-29 US claimed
EP-0661291-A1 Solid phase synthesis of oligoribonucleotide HOECHST AKTIENGESELLSCHAFT (DE) 1995-07-05 EP claimed
EP-0653439-A2 Stabilized oligonucleotids and the use thereof HOECHST AKTIENGESELLSCHAFT (DE) 1995-05-17 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260144879-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS HAVCR2, NR1H4, NR1H3 PYGM 4730/4885TK2 696/4885SLC28A1 74/4885
US-20230323399-A1 METHODS AND PRODUCTS FOR TRANSFECTING CELLS NSUN3, STING1, NFATC1 PYGM 2631/4885TK2 309/4885SLC28A1 784/4885
US-20230373903-A1 CATIONIC LIPIDS AND TRANSFECTION METHODS CETP, NPC1L1, NPC1 PYGM 4509/4885TK2 671/4885SLC28A1 321/4885
US-12384740-B2 Cationic lipids and transfection methods CETP, NPC1L1, NPC1 PYGM 4509/4885TK2 671/4885SLC28A1 321/4885
US-20230304044-A1 METHODS AND PRODUCTS FOR TRANSFECTING CELLS NSUN3, STING1, NFATC1 PYGM 2631/4885TK2 309/4885SLC28A1 784/4885
US-11814333-B2 Cationic lipids and transfection methods CETP, NPC1L1, NPC1 PYGM 4509/4885TK2 671/4885SLC28A1 321/4885
US-20260049338-A1 METHODS AND PRODUCTS FOR TRANSFECTING CELLS NSUN2, RNGTT, RNMT PYGM 3223/4885TK2 454/4885SLC28A1 228/4885
US-20240139325-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS SLC10A1, HAVCR2, HDGF PYGM 3199/4885TK2 59/4885SLC28A1 252/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.