SCHEMBL7122099

SCHEMBL7122099

O=C1C[C@@H](C(=O)OCc2ccccc2)N(C(c2ccccc2)(c2ccccc2)c2ccccc2)C1

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FKBP1A P62942 8/20 0.44
HPGD P15428 1/20 0.41
CYP3A4 P08684 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
HTR2C P28335 1/20 0.40
ELANE P08246 1/20 0.39
FABP7 O15540 1/20 0.39
FABP5 Q01469 1/20 0.39
TDP1 Q9NUW8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14762600 0.86 ALDH1A1 (0.41)
SCHEMBL9367912 0.83 FKBP1A (0.45) FKBP1AHPGDHTR2CFABP7FABP5
SCHEMBL7362332 0.83 FKBP1A (0.45) FKBP1AHPGDHTR2CFABP7FABP5
SCHEMBL31696756 0.82 MMP2 (0.55) FKBP1ACYP2C19
SCHEMBL28975603 0.81 FKBP1A (0.49) FKBP1ACYP2C19HTR2CFABP7FABP5
SCHEMBL28975604 0.81 FKBP1A (0.49) FKBP1ACYP2C19HTR2CFABP7FABP5
SCHEMBL5203676 0.80 MMP2 (0.39) HPGDCYP2C19
SCHEMBL5203668 0.80 MMP2 (0.39) HPGDCYP2C19
SCHEMBL10137577 0.79 FKBP1A (0.47) FKBP1AHPGDCYP3A4CYP2C9CYP2C19
SCHEMBL994630 0.79 FKBP1A (0.50) FKBP1AHPGDCYP3A4CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030216374-A1 Antibiotic oxazolidinone derivatives SYNGENTA LIMITED (GB) 2003-11-20 US disclosed
US-6605630-B1 Active against drug resistant gram positive pathogens SYNGENTA LIMITED (GB) 2003-08-12 US disclosed
EP-1005468-A1 ANTIBIOTIC OXAZOLIDINONE DERIVATIVES ZENECA LIMITED (GB) 2000-06-07 EP disclosed
WO-1999010342-A1 ANTIBIOTIC OXAZOLIDINONE DERIVATIVES ZENECA LIMITED (GB) 1999-03-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030216374-A1 Antibiotic oxazolidinone derivatives OXA1L, HRH1, OGDH FKBP1A 1815/4885HPGD 2311/4885CYP3A4 137/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.