Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5688778 | 1.00 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2CHRM3CHRM2CHRM1 | |
| SCHEMBL5688777 | 1.00 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2CHRM3CHRM2CHRM1 | |
| SCHEMBL4629178 | 0.90 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2KEAP1NFE2L2ITGB3 | |
| SCHEMBL4629180 | 0.90 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2KEAP1NFE2L2ITGB3 | |
| SCHEMBL17923185 | 0.88 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2CHRM3CHRM2CHRM1 | |
| SCHEMBL18040347 | 0.88 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2CHRM3CHRM2CHRM1 | |
| SCHEMBL25340944 | 0.86 | CHRM3 (0.39) | ALDH1A1CHRM3CHRM2CHRM1CHRM4 | |
| SCHEMBL20595792 | 0.86 | CHRM3 (0.39) | ALDH1A1CHRM3CHRM2CHRM1CHRM4 | |
| SCHEMBL2771369 | 0.82 | KMT2A (0.44) | ALDH1A1SMN1; SMN2CHRM3 | |
| SCHEMBL31618818 | 0.82 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2CHRM3CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260055133-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR SYNTHESIS | WAVE LIFE SCIENCES LTD (SG) | 2026-02-26 | — | — | US | disclosed |
| US-12428442-B2 | Compounds, compositions and methods for synthesis | WAVE LIFE SCIENCES LTD. (SG) | 2025-09-30 | — | — | US | disclosed |
| US-20240174710-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR SYNTHESIS | WAVE LIFE SCIENCES LTD. (SG) | 2024-05-30 | — | — | US | disclosed |
| US-11718638-B2 | Compounds, compositions and methods for synthesis | WAVE LIFE SCIENCES LTD. (SG) | 2023-08-08 | — | — | US | disclosed |
| US-11718638-B2 | Compounds, compositions and methods for synthesis | WAVE LIFE SCIENCES LTD. (SG) | 2023-08-08 | — | — | US | disclosed |
| US-11718638-B2 | Compounds, compositions and methods for synthesis | WAVE LIFE SCIENCES LTD. (SG) | 2023-08-08 | — | — | US | disclosed |
| CN-115873020-A | RAS inhibitors | 锐新医药公司 | 2023-03-31 | — | — | CN | disclosed |
| US-20220356204-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR SYNTHESIS | WAVE LIFE SCIENCES LTD. (SG) | 2022-11-10 | — | — | US | disclosed |
| EP-3642182-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR SYNTHESIS | Wave Life Sciences Ltd. (SG) | 2020-04-29 | — | — | EP | disclosed |
| CN-111051281-A | Compounds, compositions and methods for synthesis | 波涛生命科学有限公司 | 2020-04-21 | — | — | CN | disclosed |
| WO-2018237194-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR SYNTHESIS | WAVE LIFE SCIENCES LTD. (SG) | 2018-12-27 | — | — | WO | disclosed |
| EP-0974670-B1 | Process for producing optically active N-substituted azetidine-2-carboxylic acid compound | SUMITOMO CHEMICAL CO (JP) | 2006-09-13 | — | — | EP | disclosed |
| EP-1308519-B1 | Process for improving optical purity of azetidine-2-carboxylic acid | SUMITOMO CHEMICAL CO (JP) | 2006-04-19 | — | — | EP | disclosed |
| EP-1308519-A1 | Process for improving optical purity of azetidine-2-carboxylic acid | Sumitomo Chemical Company, Limited (JP) | 2003-05-07 | — | — | EP | disclosed |
| EP-0855446-B1 | Process for producing optically active azetidine-2-carboxylic acid derivative | SUMITOMO CHEMICAL CO (JP) | 2003-04-09 | — | — | EP | disclosed |
| US-6410279-B1 | GENERATING PREFERENTIAL COMPOUND IN SOLUTION; OBTAIN N-SUBSTITUTED AZETIDINE-2-CARBOXYLIC ACID ESTER, INCUBATE WITH PREFERENTIAL ENZYME, RECOVER COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-06-25 | — | — | US | disclosed |
| US-6162621-A | Process for producing optically active azetidine-2-carboxylic acid derivative | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2000-12-19 | — | — | US | disclosed |
| US-6143554-A | Process for producing optically active n-substituted azetidine-2 carboxylic acid compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-11-07 | — | — | US | disclosed |
| EP-0974670-A2 | Process for producing optically active N-substituted azetidine-2-carboxylic acid compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-01-26 | — | — | EP | disclosed |
| EP-0855446-A2 | Process for producing optically active azetidine-2-carboxylic acid derivative | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1998-07-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11718638-B2 | Compounds, compositions and methods for synthesis | ALKBH1, DUT, RNGTT | ALDH1A1 2134/4885SMN1; SMN2 524/4885CHRM3 3179/4885 |
| US-20220356204-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR SYNTHESIS | ALKBH1, DUT, RNGTT | ALDH1A1 2134/4885SMN1; SMN2 524/4885CHRM3 3179/4885 |
| US-12428442-B2 | Compounds, compositions and methods for synthesis | ALKBH1, DUT, RNGTT | ALDH1A1 2134/4885SMN1; SMN2 524/4885CHRM3 3179/4885 |
| US-20260055133-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR SYNTHESIS | NSUN2, NSUN3, NOP2 | ALDH1A1 3107/4885SMN1; SMN2 572/4885CHRM3 1473/4885 |
| US-20240174710-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR SYNTHESIS | ALKBH1, DUT, RNGTT | ALDH1A1 2134/4885SMN1; SMN2 524/4885CHRM3 3179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.