SCHEMBL2897587

SCHEMBL2897587

Cc1[c]cnn1-c1ccccc1C(F)F

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 1/20 0.36
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
FAAH O00519 1/20 0.30
MGLL Q99685 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2350243 0.78 KCNN4 (0.41) KCNN4MGLL
SCHEMBL2897551 0.78 ALDH1A1 (0.42) L3MBTL1MGLL
SCHEMBL2900638 0.77 HCAR1 (0.35) KCNN4TDP1L3MBTL1
SCHEMBL2897578 0.77 DRD1 (0.30)
SCHEMBL2895171 0.77 KCNN4 (0.30) KCNN4
SCHEMBL2902951 0.77
SCHEMBL1903586 0.75 MAPK14 (0.40) KCNN4MGLL
SCHEMBL2903061 0.75 HCAR1 (0.42) KCNN4L3MBTL1MGLL
SCHEMBL2902947 0.71 ALDH1A1 (0.37) TDP1L3MBTL1MGLL
SCHEMBL316519 0.70 RAB9A (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100305124-A1 Acylated Aminopyridine and Aminopyridazine Insecticides BAYER CROPSCIENCE AG (DE) 2010-12-02 US disclosed
EP-2236505-A1 Acylated aminopyridines and pyridazines as insecticides Bayer CropScience AG (DE) 2010-10-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100305124-A1 Acylated Aminopyridine and Aminopyridazine Insecticides AAAS, DDT, QDPR KCNN4 362/4885TDP1 1244/4885L3MBTL1 1263/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.