SCHEMBL28976996

SCHEMBL28976996

Brc1cccc(-c2c3ccccc3c(-c3ccccc3)c3cc(-c4ccccc4)ccc23)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.42
MAPK1 P28482 2/20 0.42
GABRA1 P14867 2/20 0.41
GABRG2 P18507 2/20 0.41
GABRB3 P28472 2/20 0.41
GABRA5 P31644 2/20 0.41
GABRA3 P34903 2/20 0.41
NPC1 O15118 3/20 0.41
RAB9A P51151 3/20 0.41
TSHR P16473 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
TP53 P04637 1/20 0.41
GABRP O00591 1/20 0.39
GABRD O14764 1/20 0.39
GABRB1 P18505 1/20 0.39
GABRA2 P47869 1/20 0.39
GABRB2 P47870 1/20 0.39
GABRA4 P48169 1/20 0.39
GABRE P78334 1/20 0.39
GABRA6 Q16445 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30288863 1.00 ALDH1A1 (0.42) ALDH1A1MAPK1GABRA1GABRG2GABRB3
SCHEMBL17701247 0.98 ALDH1A1 (0.43) ALDH1A1MAPK1GABRA1GABRG2GABRB3
SCHEMBL390858 0.96 GABRG2 (0.44) ALDH1A1MAPK1GABRA1GABRG2GABRB3
SCHEMBL5191562 0.93 ALDH1A1 (0.48) ALDH1A1MAPK1GABRA1GABRG2GABRB3
SCHEMBL30392309 0.89 NPC1 (0.48) ALDH1A1MAPK1GABRA1GABRG2GABRB3
SCHEMBL459006 0.89 NPC1 (0.48) ALDH1A1MAPK1GABRA1GABRG2GABRB3
SCHEMBL391049 0.87 MAPK1 (0.58) ALDH1A1MAPK1NPC1RAB9ASMN1; SMN2
SCHEMBL19283290 0.87 MAPK1 (0.58) ALDH1A1MAPK1NPC1RAB9ASMN1; SMN2
SCHEMBL12791336 0.85 ALDH1A1 (0.54) ALDH1A1MAPK1GABRA1GABRG2GABRB3
SCHEMBL28924402 0.85 ALDH1A1 (0.54) ALDH1A1MAPK1GABRA1GABRG2GABRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116082369-A Organic electroluminescent material based on triazolopyridine and organic electroluminescent device 武汉尚赛光电科技有限公司 2023-05-09 CN disclosed
CN-110452689-B Triazolopyridine-based organic electroluminescent material and organic electroluminescent device 武汉尚赛光电科技有限公司 2023-02-28 CN disclosed