SCHEMBL390858

SCHEMBL390858

Brc1cccc(-c2ccc3c(-c4ccccc4)c4ccccc4c(-c4ccccc4)c3c2)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRG2 P18507 4/20 0.44
GABRB3 P28472 4/20 0.44
GABRA5 P31644 4/20 0.44
GABRA3 P34903 4/20 0.44
GABRA1 P14867 2/20 0.44
NPC1 O15118 3/20 0.43
RAB9A P51151 3/20 0.43
TSHR P16473 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
TP53 P04637 1/20 0.43
GABRP O00591 1/20 0.41
GABRD O14764 1/20 0.41
GABRB1 P18505 1/20 0.41
GABRA2 P47869 1/20 0.41
GABRB2 P47870 1/20 0.41
GABRA4 P48169 1/20 0.41
GABRE P78334 1/20 0.41
GABRA6 Q16445 1/20 0.41
GABRG1 Q8N1C3 1/20 0.41
GABRG3 Q99928 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28976996 0.96 ALDH1A1 (0.42) GABRG2GABRB3GABRA5GABRA3GABRA1
SCHEMBL30288863 0.96 ALDH1A1 (0.42) GABRG2GABRB3GABRA5GABRA3GABRA1
SCHEMBL17701247 0.95 ALDH1A1 (0.43) GABRG2GABRB3GABRA5GABRA3GABRA1
SCHEMBL5191562 0.92 ALDH1A1 (0.48) GABRG2GABRB3GABRA5GABRA3GABRA1
SCHEMBL459006 0.88 NPC1 (0.48) GABRG2GABRB3GABRA5GABRA3GABRA1
SCHEMBL30392309 0.88 NPC1 (0.48) GABRG2GABRB3GABRA5GABRA3GABRA1
SCHEMBL391049 0.87 MAPK1 (0.58) NPC1RAB9ASMN1; SMN2ALDH1A1MAPK1
SCHEMBL19283290 0.87 MAPK1 (0.58) NPC1RAB9ASMN1; SMN2ALDH1A1MAPK1
SCHEMBL21435746 0.86 HSD17B1 (0.43) MAPK1MAPTKDM4ETDP1L3MBTL1
SCHEMBL994958 0.86 ACHE (0.45) ALDH1A1MAPK1MAPTKDM4ETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11795182-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2023-10-24 US disclosed
US-11795182-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2023-10-24 US disclosed
US-20220106336-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, And Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2022-04-07 US disclosed
US-11236114-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2022-02-01 US disclosed
US-10833282-B2 Light-emitting element and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2020-11-10 US disclosed
US-20190256529-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2019-08-22 US disclosed
US-10233199-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2019-03-19 US disclosed
US-10071993-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-09-11 US disclosed
US-20180099983-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO, LTD. (JP) 2018-04-12 US disclosed
US-20180099983-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO, LTD. (JP) 2018-04-12 US disclosed
US-20110114928-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2011-05-19 US disclosed
US-20090058278-A1 Light-Emitting Element, Light-Emitting Device, and Electronic Appliance SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2009-03-05 US disclosed
US-20090058278-A1 Light-Emitting Element, Light-Emitting Device, and Electronic Appliance SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2009-03-05 US disclosed
US-20090058278-A1 Light-Emitting Element, Light-Emitting Device, and Electronic Appliance SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2009-03-05 US disclosed
EP-2031036-A1 Light-emitting element, light-emitting device, and electronic appliance SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-03-04 EP disclosed
CN-101378612-A Light-emitting element, light-emitting device, and electronic apparatus SEMICONDUCTOR ENERGY LAB (JP) 2009-03-04 CN disclosed
US-20090004506-A1 Anthracene Derivatives and Light-Emitting Devices Using the Anthracene Derivatives SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2009-01-01 US disclosed
US-20090004506-A1 Anthracene Derivatives and Light-Emitting Devices Using the Anthracene Derivatives SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2009-01-01 US disclosed
US-20090004506-A1 Anthracene Derivatives and Light-Emitting Devices Using the Anthracene Derivatives SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2009-01-01 US disclosed
CN-101219959-A Anthracene derivant, organic compound, illuminating device and electronic equipments SEMICONDUCTOR ENERGY LAB (JP) 2008-07-16 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10233199-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device CRY1, CCNE2, CCNE1 GABRG2 1901/4885GABRB3 3783/4885GABRA5 2624/4885
US-20110114928-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device CRY1, CCNE2, CCNE1 GABRG2 1818/4885GABRB3 3713/4885GABRA5 2521/4885
US-20180099983-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device CRY1, CCNE2, CCNE1 GABRG2 1818/4885GABRB3 3713/4885GABRA5 2521/4885
US-10833282-B2 Light-emitting element and electronic device SLC39A3, SLC19A2, SLC39A14 GABRG2 1508/4885GABRB3 738/4885GABRA5 665/4885
US-11795182-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device CRY1, CCNE2, CCNE1 GABRG2 1818/4885GABRB3 3713/4885GABRA5 2521/4885
US-11236114-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device CRY1, CCNE2, CCNE1 GABRG2 1818/4885GABRB3 3713/4885GABRA5 2521/4885
US-10071993-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SLC39A3, SULT1A1, NUTF2 GABRG2 2194/4885GABRB3 876/4885GABRA5 914/4885
US-20090004506-A1 Anthracene Derivatives and Light-Emitting Devices Using the Anthracene Derivatives CRY1, CYP1A1, GLB1 GABRG2 4756/4885GABRB3 4852/4885GABRA5 4708/4885
US-20190256529-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device CRY1, CCNE2, CCNE1 GABRG2 1818/4885GABRB3 3713/4885GABRA5 2521/4885
US-20220106336-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, And Lighting Device CRY1, CCNE2, CCNE1 GABRG2 1818/4885GABRB3 3713/4885GABRA5 2521/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.