SCHEMBL459006

SCHEMBL459006

Brc1cccc(-c2c3ccccc3c(-c3ccccc3)c3ccccc23)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.48
TSHR P16473 2/20 0.48
RAB9A P51151 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
TP53 P04637 1/20 0.48
GABRA1 P14867 2/20 0.45
GABRG2 P18507 2/20 0.45
GABRB3 P28472 2/20 0.45
GABRA5 P31644 2/20 0.45
GABRA3 P34903 2/20 0.45
GABRP O00591 1/20 0.45
GABRD O14764 1/20 0.45
GABRB1 P18505 1/20 0.45
GABRA2 P47869 1/20 0.45
GABRB2 P47870 1/20 0.45
GABRA4 P48169 1/20 0.45
GABRE P78334 1/20 0.45
GABRA6 Q16445 1/20 0.45
GABRG1 Q8N1C3 1/20 0.45
GABRG3 Q99928 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30392309 1.00 NPC1 (0.48) NPC1TSHRRAB9ASMN1; SMN2TP53
SCHEMBL9972008 0.96 GABRA1 (0.47) NPC1TSHRRAB9ASMN1; SMN2TP53
SCHEMBL28441407 0.94 NPC1 (0.47) NPC1TSHRRAB9ASMN1; SMN2TP53
SCHEMBL5191562 0.92 ALDH1A1 (0.48) NPC1TSHRRAB9ASMN1; SMN2TP53
SCHEMBL28976996 0.89 ALDH1A1 (0.42) NPC1TSHRRAB9ASMN1; SMN2TP53
SCHEMBL30288863 0.89 ALDH1A1 (0.42) NPC1TSHRRAB9ASMN1; SMN2TP53
SCHEMBL19497384 0.89 RAB9A (0.53) NPC1TSHRRAB9ASMN1; SMN2TP53
SCHEMBL390858 0.88 GABRG2 (0.44) NPC1TSHRRAB9ASMN1; SMN2TP53
SCHEMBL17701247 0.87 ALDH1A1 (0.43) NPC1TSHRRAB9ASMN1; SMN2TP53
SCHEMBL2713323 0.87 NPC1 (0.42) NPC1TSHRRAB9ASMN1; SMN2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240237383-A1 ORGANIC ELECTROLUMINESCENT DEVICE SFC CO., LTD. (KR) 2024-07-11 US disclosed
CN-118159908-A Photosensitive element and method for forming resist pattern 旭化成株式会社 2024-06-07 CN disclosed
US-11991928-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2024-05-21 US disclosed
WO-2024085254-A1 PHOTOSENSITIVE RESIN COMPOSITION, PHOTOSENSITIVE RESIN MULTILAYER BODY, AND METHOD FOR FORMING RESIST PATTERN 旭化成株式会社 2024-04-25 WO disclosed
CN-117164478-A Method for preparing anthracycline derivative 苏州大学 2023-12-05 CN disclosed
WO-2023074325-A1 PHOTOSENSITIVE ELEMENT, AND METHOD FOR FORMING RESIST PATTERN 旭化成株式会社 2023-05-04 WO disclosed
US-20230034532-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-02-02 US disclosed
US-20220310933-A1 ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING AN AZINE COMPOUND AND A RARE EARTH METAL, RARE EARTH METAL COMPOUND, AND/OR RARE EARTH METAL COMPLEX AND AN ELECTRONIC EQUIPMENT COMPRISING SAID ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2022-09-29 US disclosed
EP-4060756-A1 AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING AN AZINE COMPOUND AND A RARE EARTH METAL, RARE EARTH METAL COMPOUND, AND/OR RARE EARTH METAL COMPLEX AND AN ELECTRONIC EQUIPMENT COMPRISING SAID ORGANIC ELECTROLUMINESCENCE DEVICE Idemitsu Kosan Co., Ltd. (JP) 2022-09-21 EP disclosed
EP-3876296-A1 ORGANIC LIGHT-EMITTING DEVICE Samsung Electronics Co., Ltd. (KR) 2021-09-08 EP disclosed
US-7732065-B2 Anthracene derivative compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2010-06-08 US disclosed
US-7718278-B2 Anthrancene derivative compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2010-05-18 US disclosed
US-7718278-B2 Anthrancene derivative compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2010-05-18 US disclosed
US-20090317539-A1 Composition, Method for Manufacturing Thin Film, and Method for Manufacturing Light-Emitting Element SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2009-12-24 US disclosed
US-20090317539-A1 Composition, Method for Manufacturing Thin Film, and Method for Manufacturing Light-Emitting Element SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2009-12-24 US disclosed
US-20090317539-A1 Composition, Method for Manufacturing Thin Film, and Method for Manufacturing Light-Emitting Element SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2009-12-24 US disclosed
US-20080122346-A1 ANTHRANCENE DERIVATIVE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-05-29 US disclosed
US-20080122346-A1 ANTHRANCENE DERIVATIVE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-05-29 US disclosed
US-20080111478-A1 ANTHRACENE DERIVATIVE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-05-15 US disclosed
US-20080111478-A1 ANTHRACENE DERIVATIVE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-05-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11991928-B2 Heterocyclic compound and organic light-emitting device including the same NR0B1, CRY1, CCNT1 NPC1 3063/4885TSHR 2799/4885RAB9A 1847/4885
US-20080111478-A1 ANTHRACENE DERIVATIVE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME AR, CYP1A1, ARL1 NPC1 3020/4885TSHR 3785/4885RAB9A 1769/4885
US-20220310933-A1 ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING AN AZINE COMPOUND AND A RARE EARTH METAL, RARE EARTH METAL COMPOUND, AND/OR RARE EARTH METAL COMPLEX AND AN ELECTRONIC EQUIPMENT COMPRISING SAID ORGANIC ELECTROLUMINESCENCE DEVICE SLC30A7, SLC39A7, SLC39A3 NPC1 422/4885TSHR 2458/4885RAB9A 488/4885
US-20080122346-A1 ANTHRANCENE DERIVATIVE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME AR, CRY2, ANTXR2 NPC1 4078/4885TSHR 3800/4885RAB9A 1282/4885
US-20230034532-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME NR0B1, CRY1, CCNT1 NPC1 3063/4885TSHR 2799/4885RAB9A 1847/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.