Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MAT2A | P31153 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29417527 | 0.84 | ADORA2A (0.41) | ADORA2AADORA1KDM4EALDH1A1LMNA | |
| SCHEMBL28978569 | 0.83 | ADORA2A (0.42) | ADORA2AADORA1KDM4EALDH1A1LMNA | |
| SCHEMBL29417532 | 0.82 | MAT2A (0.50) | KDM4EALDH1A1MAPTRECQLMAT2A | |
| SCHEMBL28978594 | 0.82 | MAT2A (0.50) | KDM4EALDH1A1MAPTRECQLMAT2A | |
| SCHEMBL8804203 | 0.77 | FEN1 (0.54) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL28978823 | 0.76 | ALDH1A1 (0.37) | KDM4EALDH1A1MAPTRECQLMEN1 | |
| SCHEMBL29417557 | 0.76 | MAT2A (0.42) | ALDH1A1MAT2AMEN1KMT2AGAA | |
| SCHEMBL29417554 | 0.76 | ALDH1A1 (0.37) | KDM4EALDH1A1MAPTRECQLMEN1 | |
| SCHEMBL28978832 | 0.76 | MAT2A (0.42) | ALDH1A1MAT2AMEN1KMT2AGAA | |
| SCHEMBL16088478 | 0.75 | MEN1 (0.39) | KDM4EALDH1A1LMNAMAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916778-A | Methionine adenosyltransferase inhibitor, preparation method and application thereof | 赛诺哈勃药业（成都）有限公司 | 2023-04-04 | — | — | CN | disclosed |
| WO-2022053022-A1 | METHIONINE ADENOSYLTRANSFERASE INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 赛诺哈勃药业（成都）有限公司 | 2022-03-17 | — | — | WO | disclosed |