Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.35 |
| ▸ | GAA | P10253 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 4/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28978823 | 1.00 | ALDH1A1 (0.37) | ALDH1A1POLBTSHRSMN1; SMN2HPGD | |
| SCHEMBL28978807 | 0.86 | ALDH1A1 (0.38) | ALDH1A1POLBTSHRSMN1; SMN2HPGD | |
| SCHEMBL29417532 | 0.82 | MAT2A (0.50) | ALDH1A1POLBTSHRSMN1; SMN2HPGD | |
| SCHEMBL28978594 | 0.82 | MAT2A (0.50) | ALDH1A1POLBTSHRSMN1; SMN2HPGD | |
| SCHEMBL28978832 | 0.81 | MAT2A (0.42) | ALDH1A1POLBGAAMEN1KMT2A | |
| SCHEMBL29417557 | 0.81 | MAT2A (0.42) | ALDH1A1POLBGAAMEN1KMT2A | |
| SCHEMBL8804203 | 0.77 | FEN1 (0.54) | ALDH1A1TSHRSMN1; SMN2KDM4EGAA | |
| SCHEMBL28978593 | 0.76 | ADORA2A (0.43) | ALDH1A1SMN1; SMN2KDM4EGAAMEN1 | |
| SCHEMBL16088478 | 0.73 | MEN1 (0.39) | ALDH1A1TSHRSMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL30608050 | 0.68 | MAPK8 (0.49) | ALDH1A1POLBCYP1A2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022053022-A1 | METHIONINE ADENOSYLTRANSFERASE INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 赛诺哈勃药业（成都）有限公司 | 2022-03-17 | — | — | WO | disclosed |