Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | USP14 | P54578 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAT2A | P31153 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29417517 | 0.87 | CTSK (0.43) | CTSKALDH1A1KDM4EUSP14KMT2A | |
| SCHEMBL28978596 | 0.87 | CTSK (0.43) | CTSKALDH1A1KDM4EUSP14KMT2A | |
| SCHEMBL30358964 | 0.81 | MAT2A (0.48) | CTSKALDH1A1KDM4EKMT2AMAT2A | |
| SCHEMBL28978826 | 0.81 | MAT2A (0.48) | CTSKALDH1A1KDM4EKMT2AMAT2A | |
| SCHEMBL28978580 | 0.78 | MAT2A (0.41) | CTSKALDH1A1KDM4EKMT2AMAT2A | |
| SCHEMBL29417542 | 0.71 | MAT2A (0.48) | CTSKALDH1A1KDM4EKMT2AMAT2A | |
| SCHEMBL30608124 | 0.71 | MAT2A (0.48) | CTSKALDH1A1KDM4EMAT2ALMNA | |
| SCHEMBL26125895 | 0.71 | MAT2A (0.48) | CTSKALDH1A1KDM4EMAT2ALMNA | |
| SCHEMBL28978808 | 0.71 | MAT2A (0.48) | CTSKALDH1A1KDM4EKMT2AMAT2A | |
| SCHEMBL8178799 | 0.70 | KDM4E (0.46) | ALDH1A1KDM4EKMT2ALMNAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916778-A | Methionine adenosyltransferase inhibitor, preparation method and application thereof | 赛诺哈勃药业（成都）有限公司 | 2023-04-04 | — | — | CN | disclosed |
| WO-2022053022-A1 | METHIONINE ADENOSYLTRANSFERASE INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 赛诺哈勃药业（成都）有限公司 | 2022-03-17 | — | — | WO | disclosed |