Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.43 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.38 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28860962 | 0.88 | HSD17B10 (0.46) | TP53CNR1CNR2ALDH1A1KDM4E | |
| SCHEMBL23989067 | 0.84 | ALKBH5 (0.56) | ALKBH5FTOCNR1CNR2ALDH1A1 | |
| SCHEMBL28225867 | 0.83 | L3MBTL1 (0.49) | ALKBH5FTOTP53SLC2A1ALDH1A1 | |
| SCHEMBL21973672 | 0.77 | ALKBH5 (0.49) | ALKBH5FTOCNR1CNR2ALDH1A1 | |
| SCHEMBL21566359 | 0.77 | TDP1 (0.49) | ALKBH5FTOCNR1CNR2ALDH1A1 | |
| SCHEMBL28979151 | 0.75 | KDM4E (0.50) | TP53CNR1CNR2ALDH1A1KMT2A | |
| SCHEMBL1010313 | 0.75 | ALDH1A1 (0.59) | TP53SLC2A1ALDH1A1CYP2A6KMT2A | |
| SCHEMBL490291 | 0.75 | ALDH1A1 (0.50) | CNR1CNR2ALDH1A1CYP2A6KMT2A | |
| SCHEMBL29476055 | 0.75 | ALDH1A1 (0.50) | CNR1CNR2ALDH1A1CYP2A6KMT2A | |
| SCHEMBL27120032 | 0.75 | MEN1 (0.40) | ALKBH5FTOALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108129382-B | Carbazole derivative and application thereof | 北京鼎材科技有限公司 | 2022-07-19 | — | — | CN | disclosed |