Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CDC25B | P30305 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | FADS1 | O60427 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CCR4 | P51679 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28979150 | 0.88 | ALKBH5 (0.43) | ALDH1A1TP53HPGDCNR1CNR2 | |
| SCHEMBL28979151 | 0.86 | KDM4E (0.50) | HSD17B10CDC25BALDH1A1TP53CYP3A4 | |
| SCHEMBL21566359 | 0.81 | TDP1 (0.49) | HSD17B10ALDH1A1HPGDTSHRATM | |
| SCHEMBL490357 | 0.80 | FADS1 (0.49) | HSD17B10CDC25BALDH1A1TP53CYP3A4 | |
| SCHEMBL490291 | 0.79 | ALDH1A1 (0.50) | HSD17B10ALDH1A1HPGDTSHRATM | |
| SCHEMBL29476055 | 0.79 | ALDH1A1 (0.50) | HSD17B10ALDH1A1HPGDTSHRATM | |
| SCHEMBL28956380 | 0.79 | KDM4E (0.45) | HSD17B10CDC25BALDH1A1TP53CYP3A4 | |
| SCHEMBL20149454 | 0.78 | POLB (0.49) | HSD17B10ALDH1A1HPGDTSHRATM | |
| SCHEMBL14666574 | 0.78 | TDP1 (0.50) | HSD17B10ALDH1A1HPGDTSHRATM | |
| Benzene SCHEMBL28312148 | 0.77 | ALDH1A1 (0.53) | HSD17B10ALDH1A1HPGDTSHRATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108129382-B | Carbazole derivative and application thereof | 北京鼎材科技有限公司 | 2022-07-19 | — | — | CN | disclosed |
| CN-108129382-A | Carbazole derivates and its application | 北京鼎材科技有限公司 | 2018-06-08 | — | — | CN | disclosed |