Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 7/20 | 0.66 |
| ▸ | CTSL | P07711 | 5/20 | 0.66 |
| ▸ | CTSK | P43235 | 3/20 | 0.66 |
| ▸ | METAP2 | P50579 | 1/20 | 0.55 |
| ▸ | METAP1 | P53582 | 1/20 | 0.55 |
| ▸ | HTRA1 | Q92743 | 12/20 | 0.54 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17859965 | 1.00 | CTSS (0.66) | CTSSCTSLCTSKMETAP2METAP1 | |
| SCHEMBL29397792 | 1.00 | CTSS (0.66) | CTSSCTSLCTSKMETAP2METAP1 | |
| SCHEMBL17843401 | 0.87 | GRN (0.62) | CTSSCTSLCTSKMETAP2METAP1 | |
| SCHEMBL17843413 | 0.87 | GRN (0.62) | CTSSCTSLCTSKMETAP2METAP1 | |
| SCHEMBL30334963 | 0.87 | GRN (0.62) | CTSSCTSLCTSKMETAP2METAP1 | |
| SCHEMBL24249641 | 0.85 | CTSL (0.51) | CTSSCTSLCTSKMETAP2METAP1 | |
| SCHEMBL28979538 | 0.82 | CTSS (0.52) | CTSSCTSLCTSKMETAP2METAP1 | |
| SCHEMBL5525446 | 0.82 | CTSS (0.78) | CTSSCTSLCTSKMETAP2METAP1 | |
| SCHEMBL21536106 | 0.81 | HTRA1 (0.58) | CTSSCTSLCTSKHTRA1 | |
| SCHEMBL28979527 | 0.81 | HTRA1 (0.58) | CTSSCTSLCTSKHTRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563033-B | Aliphatic prolinamide derivatives | 奥瑞恩眼科有限责任公司 | 2023-04-04 | — | — | CN | disclosed |