Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.51 |
| ▸ | CTSS | P25774 | 2/20 | 0.51 |
| ▸ | CTSK | P43235 | 2/20 | 0.51 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.50 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.50 |
| ▸ | BDKRB2 | P30411 | 2/20 | 0.44 |
| ▸ | GRN | P28799 | 1/20 | 0.43 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.43 |
| ▸ | HTRA1 | Q92743 | 6/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28979552 | 0.85 | CTSS (0.66) | CTSLCTSSCTSKHTRA1CTSB | |
| SCHEMBL29397792 | 0.85 | CTSS (0.66) | CTSLCTSSCTSKHTRA1CTSB | |
| SCHEMBL17859965 | 0.85 | CTSS (0.66) | CTSLCTSSCTSKHTRA1CTSB | |
| SCHEMBL1122538 | 0.76 | BDKRB2 (0.50) | CTSLCTSSTAS1R3TAS1R1BDKRB2 | |
| SCHEMBL1123215 | 0.75 | TAS1R3 (0.53) | CTSLCTSSCTSKTAS1R3TAS1R1 | |
| SCHEMBL1123156 | 0.75 | GPR132 (0.58) | CTSLCTSSCTSKBDKRB2CTSB | |
| SCHEMBL17843413 | 0.73 | GRN (0.62) | CTSLCTSSCTSKGRNSORT1 | |
| SCHEMBL30334963 | 0.73 | GRN (0.62) | CTSLCTSSCTSKGRNSORT1 | |
| SCHEMBL17843401 | 0.73 | GRN (0.62) | CTSLCTSSCTSKGRNSORT1 | |
| SCHEMBL1123253 | 0.71 | GPR132 (0.65) | CTSLCTSSCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3472130-B1 | ALIPHATIC PROLINAMIDE DERIVATIVES | Orion Ophthalmology LLC (US) | 2022-02-16 | — | — | EP | disclosed |