Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Palmitamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | FAAH | O00519 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Octadecanoic Acid Amide SCHEMBL29142149 | 0.91 | FAAH (0.42) | SOAT1MEN1FAAHKMT2ATP53 | |
| Hydrochloric Acid SCHEMBL1958103 | 0.85 | SOAT1 (0.46) | SOAT1MEN1FAAHKMT2ATP53 | |
| SCHEMBL4660135 | 0.83 | SOAT1 (0.47) | SOAT1MEN1FAAHKMT2ATP53 | |
| Palmitamide SCHEMBL3831146 | 0.80 | SOAT1 (0.55) | SOAT1MEN1FAAHKMT2ATP53 | |
| Hydrochloric Acid SCHEMBL1705678 | 0.80 | SOAT1 (0.55) | SOAT1MEN1FAAHKMT2ATP53 | |
| Hydrochloric Acid SCHEMBL28807747 | 0.80 | SOAT1 (0.55) | SOAT1MEN1FAAHKMT2ATP53 | |
| Octadecanoic Acid Amide SCHEMBL5346586 | 0.80 | SOAT1 (0.55) | SOAT1MEN1FAAHKMT2ATP53 | |
| Octadecanoic Acid Amide SCHEMBL15533985 | 0.80 | SOAT1 (0.63) | SOAT1MEN1FAAHKMT2ATP53 | |
| Octadecanoic Acid Amide SCHEMBL28799777 | 0.79 | SOAT1 (0.53) | SOAT1MEN1FAAHKMT2ATP53 | |
| Palmitamide SCHEMBL28243343 | 0.79 | SOAT1 (0.53) | SOAT1MEN1FAAHKMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112226225-B | Temperature-resistant and salt-resistant surfactant composition for pressure reduction and injection increase of water injection well of low-permeability oil reservoir and preparation method and application thereof | 中国石油化工股份有限公司 | 2023-04-07 | — | — | CN | disclosed |