Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10973432 | 0.74 | NOTUM (0.55) | ALDH1A1HPGDNOTUMRAB9AL3MBTL1 | |
| SCHEMBL30371592 | 0.74 | NOTUM (0.55) | ALDH1A1HPGDNOTUMRAB9AL3MBTL1 | |
| SCHEMBL4630556 | 0.72 | SLC6A2 (0.36) | ALDH1A1HPGDPPARGPPARDPPARA | |
| SCHEMBL4048895 | 0.70 | NOTUM (0.42) | ALDH1A1HPGDPPARGPPARDPPARA | |
| SCHEMBL4167876 | 0.70 | NOTUM (0.39) | ALDH1A1HPGDPPARGPPARDPPARA | |
| SCHEMBL16234652 | 0.70 | ADRA2A (0.45) | ALDH1A1HPGDNOTUML3MBTL1KDM4E | |
| SCHEMBL30109124 | 0.70 | NOTUM (0.39) | ALDH1A1HPGDPPARGPPARDPPARA | |
| SCHEMBL28980350 | 0.70 | FABP4 (0.41) | ALDH1A1HPGDPPARGPPARDPPARA | |
| SCHEMBL28798997 | 0.68 | NOTUM (0.39) | ALDH1A1HPGDPPARGPPARDPPARA | |
| SCHEMBL16234638 | 0.68 | P2RX7 (0.44) | ALDH1A1HPGDNOTUMKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894326-B | 2, 3-Hydrogen substituted aminoindole derivative, preparation method and application thereof | 佛山大学 | 2025-02-11 | — | — | CN | disclosed |
| CN-115894326-A | 2,3-hydrogen substituted aminoindole derivative, preparation method and application thereof | 佛山科学技术学院 | 2023-04-04 | — | — | CN | disclosed |