Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 2/20 | 0.46 |
| ▸ | SKP1 | P63208 | 2/20 | 0.46 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.46 |
| ▸ | RET | P07949 | 7/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | ADK | P55263 | 1/20 | 0.42 |
| ▸ | SMO | Q99835 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | WNT3A | P56704 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28981151 | 0.85 | CKS1B (0.48) | CKS1BSKP1SKP2RETGPR119 | |
| SCHEMBL5916462 | 0.80 | ADK (0.58) | CKS1BSKP1SKP2RETGPR119 | |
| SCHEMBL28981154 | 0.79 | CKS1B (0.51) | CKS1BSKP1SKP2RETGPR119 | |
| SCHEMBL31129873 | 0.79 | MAP4K4 (0.52) | CKS1BSKP1SKP2RETGPR119 | |
| SCHEMBL23560773 | 0.79 | GPR119 (0.53) | RETGPR119 | |
| SCHEMBL14938608 | 0.77 | MAP4K4 (0.52) | CKS1BSKP1SKP2RETGPR119 | |
| SCHEMBL25309158 | 0.77 | SMO (0.54) | CKS1BSKP1SKP2RETGPR119 | |
| SCHEMBL17978916 | 0.77 | CKS1B (0.51) | CKS1BSKP1SKP2RETGPR119 | |
| SCHEMBL2142161 | 0.77 | CKS1B (0.51) | CKS1BSKP1SKP2RETGPR119 | |
| SCHEMBL29421852 | 0.77 | CKS1B (0.51) | CKS1BSKP1SKP2RETGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115772170-A | Pyrazolo [1,5-a ] pyridine derivative and preparation method and application thereof | 徐诺药业(南京)有限公司 | 2023-03-10 | — | — | CN | disclosed |