Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAAO | P46952 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28739998 | 0.98 | HAAO (0.41) | HAAOCYP1A2ALDH1A1KDM4EHPGD | |
| SCHEMBL7130116 | 0.86 | CYP1A2 (0.46) | HAAOCYP1A2ALDH1A1KDM4EHPGD | |
| SCHEMBL1936626 | 0.84 | CYP1A2 (0.44) | HAAOCYP1A2ALDH1A1KDM4EHPGD | |
| SCHEMBL11320085 | 0.81 | SIRT3 (0.41) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL27661072 | 0.81 | HAAO (0.41) | HAAOCYP1A2ALDH1A1KDM4EHPGD | |
| SCHEMBL3112547 | 0.81 | CYP1A2 (0.41) | HAAOCYP1A2ALDH1A1KDM4EHPGD | |
| SCHEMBL28033212 | 0.79 | CYP1A2 (0.48) | HAAOCYP1A2ALDH1A1KDM4EHPGD | |
| SCHEMBL29370019 | 0.79 | CYP1A2 (0.48) | HAAOCYP1A2ALDH1A1KDM4EHPGD | |
| SCHEMBL242262 | 0.79 | CYP1A2 (0.48) | HAAOCYP1A2ALDH1A1KDM4EHPGD | |
| SCHEMBL16107785 | 0.79 | EPRS1 (0.40) | HAAOCYP1A2ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114394952-A | Vadimezan process impurity compound, preparation method and application | 成都大学 | 2022-04-26 | — | — | CN | claimed |
| CN-114394952-A | Vadimezan process impurity compound, preparation method and application | 成都大学 | 2022-04-26 | — | — | CN | disclosed |
| US-8350065-B2 | 5,6-dimethyl xanthone-4-acetic acid derivatives and method of preparing the same | GRAND PHARMA (CHINA) CO., LTD. (CN) | 2013-01-08 | — | — | US | disclosed |
| US-8350065-B2 | 5,6-dimethyl xanthone-4-acetic acid derivatives and method of preparing the same | GRAND PHARMA (CHINA) CO., LTD. (CN) | 2013-01-08 | — | — | US | disclosed |
| US-20100286254-A1 | CRYSTALLINE FORMS OF DMXAA SODIUM SALT | ANTISOMA RESEARCH LIMITED (GB) | 2010-11-11 | — | — | US | disclosed |
| CN-101878206-A | Crystalline forms of (5, 6-dimethyl-9-oxo-9H-xanthen-4-yl) acetic acid sodium salt | ANTISOMA RES LTD | 2010-11-03 | — | — | CN | disclosed |
| EP-2205580-A1 | CRYSTALLINE FORMS OF DMXAA SODIUM SALT | Antisoma Research Limited (GB) | 2010-07-14 | — | — | EP | disclosed |
| EP-2196463-A1 | PREPARATION OF 5,6-DIMETHYLXANTHONE-4-ACETIC ACID, THE DERIVATIVES PREPARED AND PHARMACEUTICAL FORMULATIONS THEREOF | Wuhan Grand Pharmaceutical Group Co., Ltd (CN) | 2010-06-16 | — | — | EP | disclosed |
| US-20100099754-A1 | 5,6-DIMETHYL XANTHONE-4-ACETIC ACID DERIVATIVES AND METHOD OF PREPARING THE SAME | GRAND PHARMA (CHINA) CO., LTD. (CN) | 2010-04-22 | — | — | US | disclosed |
| US-20100099754-A1 | 5,6-DIMETHYL XANTHONE-4-ACETIC ACID DERIVATIVES AND METHOD OF PREPARING THE SAME | GRAND PHARMA (CHINA) CO., LTD. (CN) | 2010-04-22 | — | — | US | disclosed |
| US-20030171367-A1 | Nitrogen-containing tricyclic compounds and drugs containing the same | EISAI CO., LTD. | 2003-09-11 | — | — | US | disclosed |
| US-6489336-B2 | PHENOTHIAZINE, ACRIDAN, ACRIDONE OXIME, ACRIDONE HYDRAZONE, OR DIBENZODIAZEPINE DERIVATIVES; TYROSINE KINASE INHIBITORS; TREATING ALLERGIC DISEASES | EISAI CO., LTD. (JP) | 2002-12-03 | — | — | US | disclosed |
| US-20020103189-A1 | Nitrogen-containing tricyclic compounds and drugs containing the same | EISAI CO., LTD. | 2002-08-01 | — | — | US | disclosed |
| US-6333322-B1 | FOR THERAPY OF ASTHMA, ALLERGIC RHINITIS, ATOPIC DERMATITIS, URTICARIA, HAY FEVER, GASTROINTESTINAL ALLERGY AND FOOD ALLERGY | EISAI CO., LTD. (JP) | 2001-12-25 | — | — | US | disclosed |
| CN-1216982-A | Nitrogenous tricycle compounds and drugs comprising same | EISAI CO LTD (JP) | 1999-05-19 | — | — | CN | disclosed |
| EP-0889037-A1 | NITROGENOUS TRICYCLIC COMPOUNDS AND DRUGS COMPRISING THE SAME | Eisai Co., Ltd. (JP) | 1999-01-07 | — | — | EP | disclosed |
| EP-0857721-A1 | ACRIDONE COMPOUNDS | Eisai Co., Ltd. (JP) | 1998-08-12 | — | — | EP | disclosed |
| EP-0181526-B1 | BENZOIC ACID DERIVATIVES | Chugai Seiyaku Kabushiki Kaisha (JP) | 1989-01-18 | — | — | EP | disclosed |
| US-4698364-A | INFECTION CONTROL | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1987-10-06 | — | — | US | disclosed |
| EP-0181526-A1 | Benzoic acid derivatives | Chugai Seiyaku Kabushiki Kaisha (JP) | 1986-05-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030171367-A1 | Nitrogen-containing tricyclic compounds and drugs containing the same | HRH2, HRH1, HRH4 | HAAO 229/4885CYP1A2 63/4885ALDH1A1 149/4885 |
| US-20020103189-A1 | Nitrogen-containing tricyclic compounds and drugs containing the same | HRH2, HRH1, HRH4 | HAAO 229/4885CYP1A2 63/4885ALDH1A1 149/4885 |
| US-20100099754-A1 | 5,6-DIMETHYL XANTHONE-4-ACETIC ACID DERIVATIVES AND METHOD OF PREPARING THE SAME | HCAR2, HAO2, HK2 | HAAO 56/4885CYP1A2 39/4885ALDH1A1 1863/4885 |
| US-20100286254-A1 | CRYSTALLINE FORMS OF DMXAA SODIUM SALT | XDH, XPA, MLX | HAAO 474/4885CYP1A2 1471/4885ALDH1A1 3217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.