Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27819314 | 0.86 | KDM4E (0.49) | KDM4EALDH1A1HPGDHSD17B10SIRT1 | |
| SCHEMBL28984268 | 0.85 | KDM4E (0.48) | KDM4EALDH1A1HPGDHSD17B10SIRT1 | |
| SCHEMBL16266644 | 0.79 | CA2 (0.36) | KDM4EALDH1A1HPGDHSD17B10SIRT1 | |
| SCHEMBL27817114 | 0.77 | ABCG2 (0.50) | KDM4EALDH1A1HPGDHSD17B10NPSR1 | |
| SCHEMBL10425234 | 0.73 | KDM4E (0.46) | KDM4EALDH1A1HPGDHSD17B10SIRT1 | |
| SCHEMBL5967632 | 0.73 | NR3C1 (0.46) | KDM4EALDH1A1HPGDHSD17B10NPSR1 | |
| SCHEMBL27655154 | 0.71 | ALDH1A1 (0.50) | KDM4EALDH1A1HPGDHSD17B10NPSR1 | |
| SCHEMBL11128427 | 0.69 | ESR2 (0.45) | ALDH1A1HPGDHSD17B10NR3C1GAA | |
| SCHEMBL18940919 | 0.69 | NPC1 (0.52) | SIRT1RAB9ANR3C1XDHABCG2 | |
| SCHEMBL10425459 | 0.68 | XDH (0.41) | KDM4EALDH1A1HPGDHSD17B10SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115770270-A | Daoluotong and its use method | 朱亚琼 | 2023-03-10 | — | — | CN | disclosed |