Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 16/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28984530 | 0.91 | ENPP2 (0.50) | ENPP2PTGDR2 | |
| SCHEMBL28984486 | 0.89 | ENPP2 (0.52) | ENPP2PTGDR2RXFP1 | |
| SCHEMBL28984477 | 0.89 | ENPP2 (0.61) | ENPP2PTGDR2 | |
| SCHEMBL28984471 | 0.89 | ENPP2 (0.50) | ENPP2 | |
| SCHEMBL28984482 | 0.89 | PTGDR2 (0.52) | ENPP2TP53PTGDR2 | |
| SCHEMBL28984478 | 0.89 | ENPP2 (0.63) | ENPP2MAPT | |
| SCHEMBL28984488 | 0.88 | MAPT (0.55) | ENPP2MAPT | |
| SCHEMBL31119382 | 0.88 | ENPP2 (0.49) | ENPP2TP53LMNA | |
| SCHEMBL30130173 | 0.88 | ENPP2 (0.49) | ENPP2TP53LMNA | |
| SCHEMBL24914417 | 0.88 | DRD2 (0.50) | ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115611896-A | Compound containing tetralone or tetrahydropyridopyrimidone skeleton and preparation method and pharmaceutical application thereof | 中国药科大学 | 2023-01-17 | — | — | CN | disclosed |