SCHEMBL2898487

SCHEMBL2898487

CC(C)NCC(N)(c1ccccc1)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.41
CYP1A2 P05177 1/20 0.41
KCNN4 O15554 3/20 0.41
TDP1 Q9NUW8 2/20 0.40
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40
TAAR1 Q96RJ0 1/20 0.39
HTR2C P28335 1/20 0.37
HRH1 P35367 1/20 0.36
ADRB2 P07550 1/20 0.36
ADRB1 P08588 1/20 0.36
ADRB3 P13945 1/20 0.36
KIF11 P52732 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9453424 0.83 KDM4E (0.39) CYP2D6CYP1A2KCNN4TDP1KDM4E
SCHEMBL17830453 0.79 TAAR1 (0.54) KCNN4TDP1KDM4EALDH1A1TAAR1
SCHEMBL12000666 0.79 TDP1 (0.43) CYP2D6CYP1A2KCNN4TDP1KDM4E
SCHEMBL22458610 0.78 SIGMAR1 (0.40) CYP2D6CYP1A2KCNN4TDP1KDM4E
SCHEMBL2897917 0.77 MAOA (0.42) TDP1ALDH1A1ADRB2ADRB1ADRB3
SCHEMBL2900188 0.76 CYP1A2 (0.39) CYP2D6CYP1A2KCNN4ALDH1A1TAAR1
SCHEMBL2903242 0.76 KCNN4 (0.46) CYP2D6CYP1A2KCNN4KDM4ETAAR1
SCHEMBL28111885 0.75 ALDH1A1 (0.40) CYP2D6CYP1A2TDP1KDM4EALDH1A1
SCHEMBL19626682 0.75 KCNN4 (0.42) CYP2D6KCNN4TDP1KDM4EALDH1A1
SCHEMBL2891291 0.72 ALDH1A1 (0.38) CYP2D6CYP1A2KDM4EALDH1A1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2215101-A1 CATIONIC TRANSITION METAL CATALYSTS Kanata Chemical Technologies Inc. (CA) 2010-08-11 EP claimed
WO-2009055912-A1 CATIONIC TRANSITION METAL CATALYSTS KANATA CHEMICAL TECHNOLOGIES INC. (CA) 2009-05-07 WO claimed
EP-2215101-A1 CATIONIC TRANSITION METAL CATALYSTS Kanata Chemical Technologies Inc. (CA) 2010-08-11 EP disclosed
WO-2009055912-A1 CATIONIC TRANSITION METAL CATALYSTS KANATA CHEMICAL TECHNOLOGIES INC. (CA) 2009-05-07 WO disclosed