SCHEMBL28985141

SCHEMBL28985141

Cc1c(CN)cccc1CC(O)O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 2/20 0.38
GABRA1 P14867 1/20 0.36
GABRB2 P47870 1/20 0.36
ESR1 P03372 1/20 0.35
KCNH2 Q12809 1/20 0.35
LOXL2 Q9Y4K0 1/20 0.34
TAAR1 Q96RJ0 3/20 0.33
SLC6A2 P23975 2/20 0.33
MAOA P21397 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
CYP2A6 P11509 1/20 0.33
ADORA2A P29274 1/20 0.33
ADORA1 P30542 1/20 0.33
PDCD1 Q15116 1/20 0.32
CD274 Q9NZQ7 1/20 0.32
DPP4 P27487 1/20 0.32
ENPP2 Q13822 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL570477 0.80 ESR1 (0.51) GABRA1GABRB2ESR1KCNH2TAAR1
SCHEMBL14115801 0.77 PDCD1 (0.53) PNMTGABRA1GABRB2LOXL2TAAR1
SCHEMBL12065441 0.72 PNMT (0.41) PNMTGABRA1GABRB2LOXL2TAAR1
SCHEMBL5398644 0.72 TRPA1 (0.50) PNMTGABRA1GABRB2TAAR1TSHR
SCHEMBL15997 0.72 TAAR1 (0.48) PNMTESR1LOXL2TAAR1CYP2A6
SCHEMBL23771351 0.71 GABRA1 (0.43) PNMTGABRA1GABRB2TAAR1SLC6A2
Hydrochloric Acid SCHEMBL8702699 0.71 TRPA1 (0.48) PNMTGABRA1GABRB2TAAR1
SCHEMBL23241554 0.71 AKR1B1 (0.48) ADORA1
SCHEMBL28476371 0.70 HSPA5 (0.39) GABRA1GABRB2TAAR1SLC6A2MAOA
Hydrochloric Acid SCHEMBL8387825 0.70 TAAR1 (0.46) PNMTESR1TAAR1CYP2A6DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115980205-A Quantitative and/or qualitative method for simultaneously measuring 54 hair dyes in hair dyeing product 江苏省食品药品监督检验研究院 2023-04-18 CN claimed