Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | CD44 | P16070 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28985141 | 0.80 | PNMT (0.38) | ESR1KCNH2TSHRGABRA1GABRB2 | |
| SCHEMBL29416116 | 0.80 | ESR1 (0.51) | ESR1KCNH2CYP3A4TSHRPIK3CA | |
| SCHEMBL19469880 | 0.80 | ESR1 (0.51) | ESR1KCNH2CYP3A4TSHRPIK3CA | |
| SCHEMBL19469882 | 0.80 | ESR1 (0.51) | ESR1KCNH2CYP3A4TSHRPIK3CA | |
| SCHEMBL635759 | 0.77 | CYP3A4 (0.56) | ESR1KCNH2CYP3A4TSHRPIK3CA | |
| SCHEMBL1907795 | 0.77 | ESR1 (0.56) | ESR1KCNH2CYP3A4TSHRPIK3CA | |
| SCHEMBL17846861 | 0.77 | ESR1 (0.52) | ESR1KCNH2CYP3A4TSHRPIK3CA | |
| SCHEMBL17846977 | 0.77 | ESR1 (0.52) | ESR1KCNH2CYP3A4TSHRPIK3CA | |
| SCHEMBL840872 | 0.76 | CYP3A4 (0.62) | ESR1KCNH2CYP3A4TSHRPIK3CA | |
| Hydrochloric Acid SCHEMBL10983053 | 0.75 | CYP3A4 (0.54) | ESR1KCNH2CYP3A4TSHRPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598179-B1 | CALCIUM PARTICLE-EMBEDDED, SNAP-TO-DOUGH, HIGH-VISCOSITY BONE CEMENT | WARSAW ORTHOPEDIC INC (US) | 2016-05-11 | — | — | EP | claimed |
| US-9107951-B2 | Calcium particle-embedded, snap-to-dough, high-viscosity bone cement | KYPHON SARL (CH) | 2015-08-18 | — | — | US | claimed |
| US-20130210960-A1 | CALCIUM PARTICLE-EMBEDDED, SNAP-TO-DOUGH, HIGH-VISCOSITY BONE CEMENT | WARSAW ORTHOPEDIC, INC (US) | 2013-08-15 | — | — | US | claimed |
| EP-2598179-A2 | CALCIUM PARTICLE-EMBEDDED, SNAP-TO-DOUGH, HIGH-VISCOSITY BONE CEMENT | Warsaw Orthopedic, Inc. (US) | 2013-06-05 | — | — | EP | claimed |
| WO-2012018612-A2 | CALCIUM PARTICLE-EMBEDDED, SNAP-TO-DOUGH, HIGH-VISCOSITY BONE CEMENT | WARSAW ORTHOPEDIC, INC. (US) | 2012-02-09 | — | — | WO | claimed |
| US-7968616-B2 | Bone cement composition and method | KYPHON SARL (CH) | 2011-06-28 | — | — | US | claimed |
| EP-1931399-B1 | BONE CEMENT COMPOSITION AND METHOD OF MAKING THE SAME | SANATIS GMBH (DE) | 2010-05-26 | — | — | EP | claimed |
| US-20090264554-A1 | BONE CEMENT COMPOSITION AND METHOD | KYPHON SARL (CH) | 2009-10-22 | — | — | US | claimed |
| EP-1931399-A2 | BONE CEMENT COMPOSITION AND METHOD OF MAKING THE SAME | Sanatis GmbH (DE) | 2008-06-18 | — | — | EP | claimed |
| WO-2007025633-A2 | BONE CEMENT COMPOSITION AND METHOD OF MAKING THE SAME | SANATIS GMBH (DE) | 2007-03-08 | — | — | WO | claimed |
| US-20070048382-A1 | Bone cement composition and method of making the same | KYPHON SARL (CH) | 2007-03-01 | — | — | US | claimed |
| EP-3368095-B1 | BONE VOID FILLER HAVING SUSTAINED THERAPEUTIC AGENT RELEASE | WARSAW ORTHOPEDIC INC (US) | 2023-09-06 | — | — | EP | disclosed |
| EP-3367974-B1 | BONE VOID FILLER HAVING CALCIUM COATINGS | WARSAW ORTHOPEDIC INC (US) | 2023-09-06 | — | — | EP | disclosed |
| CN-108770341-B | Bone void filler with calcium coating | 华沙整形外科股份有限公司 | 2021-05-25 | — | — | CN | disclosed |
| US-10603409-B2 | Bone void filler having calcium coatings | WARSAW ORTHOPEDIC, INC. (US) | 2020-03-31 | — | — | US | disclosed |
| EP-0676212-B1 | Method for forming bone cement to an implant | BRISTOL MYERS SQUIBB CO (US) | 2001-10-17 | — | — | EP | disclosed |
| US-5538514-A | Method for forming bone cement to an implant | ZIMMER, INC. (US) | 1996-07-23 | — | — | US | disclosed |
| EP-0676212-A1 | Method for forming bone cement to an implant | Bristol-Myers Squibb Company (US) | 1995-10-11 | — | — | EP | disclosed |
| US-4791150-A | Composition for use in making bone cement | BONAR COLE POLYMERS LIMITED (GB) | 1988-12-13 | — | — | US | disclosed |
| EP-0218471-A1 | Bone cement | BONAR COLE POLYMERS LIMITED (GB) | 1987-04-15 | — | — | EP | disclosed |