Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7525162 | 0.83 | ALDH1A1 (0.64) | LMNAALDH1A1TDP1L3MBTL1NFKB1 | |
| SCHEMBL5884605 | 0.82 | KMT2A (0.51) | LMNAALDH1A1KMT2AAKR1B1NFKB1 | |
| SCHEMBL7226304 | 0.80 | TSHR (0.41) | LMNAALDH1A1TDP1L3MBTL1TSHR | |
| SCHEMBL21706910 | 0.78 | AKR1B1 (0.42) | LMNAALDH1A1TDP1L3MBTL1KMT2A | |
| SCHEMBL7328673 | 0.78 | F2RL1 (0.56) | LMNAALDH1A1KMT2AAKR1B1NFKB1 | |
| SCHEMBL63490 | 0.78 | CYP4F2 (0.56) | LMNAALDH1A1TDP1L3MBTL1KMT2A | |
| SCHEMBL28012705 | 0.77 | AKR1B1 (0.49) | LMNAALDH1A1KMT2AAKR1B1NFKB1 | |
| SCHEMBL490401 | 0.77 | FFAR1 (0.56) | LMNAL3MBTL1AKR1B1NFKB1NFKB2 | |
| SCHEMBL16054397 | 0.77 | KDM4E (0.62) | LMNAALDH1A1KMT2AAKR1B1NFKB1 | |
| SCHEMBL9231052 | 0.77 | PTGS1 (0.41) | LMNAALDH1A1TDP1L3MBTL1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115819239-A | Intermediate of fibroblast growth factor receptor inhibitor and preparation method and application thereof | 无锡和誉生物医药科技有限公司 | 2023-03-21 | — | — | CN | disclosed |
| CN-115819239-A | Intermediate of fibroblast growth factor receptor inhibitor and preparation method and application thereof | 无锡和誉生物医药科技有限公司 | 2023-03-21 | — | — | CN | disclosed |