Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 11/20 | 0.40 |
| ▸ | CNR2 | P34972 | 9/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28985335 | 0.78 | LMNA (0.47) | AKR1B1ALDH1A1KMT2AL3MBTL1LMNA | |
| SCHEMBL21706782 | 0.77 | FAAH (0.54) | ALOX5KMT2ALMNATDP1HDAC1 | |
| SCHEMBL229166 | 0.77 | SMN1; SMN2 (0.50) | PTGS2CNR1CNR2ALOX5KMT2A | |
| SCHEMBL15994904 | 0.76 | KDM4E (0.50) | AKR1B1PTGS2CNR1CNR2ALOX5 | |
| SCHEMBL227344 | 0.76 | FFAR4 (0.50) | AKR1B1PTGS2CNR1CNR2ALOX5 | |
| SCHEMBL14672756 | 0.76 | MTNR1A (0.49) | AKR1B1PTGS2CNR1CNR2ALOX5 | |
| SCHEMBL21706914 | 0.75 | HDAC1 (0.54) | HDAC1HDAC6 | |
| SCHEMBL1052227 | 0.73 | PTGS2 (0.50) | PTGS2CNR1CNR2ALOX5HDAC1 | |
| SCHEMBL31329290 | 0.73 | ALOX5 (0.59) | ALOX5ALDH1A1KMT2AL3MBTL1LMNA | |
| Cyclopropane SCHEMBL11843578 | 0.72 | CNR1 (0.52) | PTGS2CNR1CNR2KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020030814-A1 | METHODS FOR DELAYING OCCURRENCE OF NEW-ONSET TYPE 2 DIABETES AND FOR SLOWING PROGRESSION OF AND TREATING TYPE 2 DIABETES | DALCOR PHARMA UK LTD., LEATHERHEAD, ZUG BRANCH (CH) | 2020-02-13 | — | — | WO | disclosed |