Sugi Predict

Sugi Predict / Compounds / SCHEMBL490401

SCHEMBL490401

SCHEMBL490401

COc1cc(CCC(=O)O)cc(OC)c1

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ FFAR1 O14842 5/20 0.56
▸ POLB P06746 2/20 0.53
▸ AKR1B1 P15121 1/20 0.49
▸ GAA P10253 1/20 0.48
▸ NFKB1 P19838 1/20 0.47
▸ NFKB2 Q00653 1/20 0.47
▸ RELA Q04206 1/20 0.47
▸ CYP19A1 P11511 1/20 0.47
▸ KEAP1 Q14145 1/20 0.47
▸ THRA P10827 1/20 0.46
▸ THRB P10828 1/20 0.46
▸ NPC1 O15118 1/20 0.46
▸ RAB9A P51151 1/20 0.46
▸ LMNA P02545 1/20 0.46
▸ L3MBTL1 Q9Y468 1/20 0.46
▸ F2RL1 P55085 1/20 0.46
▸ FFAR4 Q5NUL3 1/20 0.46
▸ HSD17B1 P14061 1/20 0.46
▸ HSD17B2 P37059 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23599377 0.89 FFAR1 (0.50) FFAR1POLBTHRATHRBNPC1
SCHEMBL227344 0.89 FFAR4 (0.50) FFAR1POLBAKR1B1CYP19A1FFAR4
SCHEMBL2390684 0.88 FFAR1 (0.49) FFAR1POLBNFKB1NFKB2RELA
SCHEMBL21098761 0.88 FFAR4 (0.51) FFAR1POLBNFKB1NFKB2RELA
SCHEMBL7328673 0.86 F2RL1 (0.56) AKR1B1GAANFKB1NFKB2RELA
SCHEMBL5275656 0.85 CNR1 (0.53) FFAR1FFAR4
SCHEMBL7794809 0.85 RXRA (0.54) FFAR1POLBNFKB1NFKB2RELA
SCHEMBL16054397 0.84 KDM4E (0.62) AKR1B1GAANFKB1NFKB2RELA
SCHEMBL28012705 0.84 AKR1B1 (0.49) AKR1B1GAANFKB1NFKB2RELA
SCHEMBL14441580 0.84 RXRA (0.56) FFAR1POLBTHRATHRBFFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111072638-B Method for preparing AZD4547, intermediate and preparation method of intermediate 上海工程技术大学 2021-03-16 — — CN claimed
CN-111072638-A Method for preparing AZD4547, intermediate and preparation method of intermediate 上海工程技术大学 2020-04-28 — — CN claimed
US-20260062393-A1 Compounds CTXT PTY LTD (AU) 2026-03-05 — — US disclosed
US-12365655-B2 Compounds CTXT PTY LTD (AU) 2025-07-22 — — US disclosed
CN-119859122-B Tyrosinase inhibitor and preparation method and application thereof 杭州师范大学 2025-06-13 — — CN disclosed
CN-112334466-B Compounds of formula (I) CTXT私人有限公司 2025-05-30 — — CN disclosed
CN-119859122-A Tyrosinase inhibitor and preparation method and application thereof 杭州师范大学 2025-04-22 — — CN disclosed
CN-115872930-B N-substituted 3, 4-dihydro-isoquinolin-1 (2H) -one derivatives, compositions thereof and use thereof in medicine 贵州医科大学 2025-02-11 — — CN disclosed
US-20240351966-A1 CLASS OF ALKYLPHENOL COMPOUNDS AND PREPARATION METHOD THEREFOR SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) 2024-10-24 — — US disclosed
CN-114728910-B Pyrazole derivative for FGFR inhibitor and preparation method thereof 上海奕拓医药科技有限责任公司 2024-05-14 — — CN disclosed
EP-4353706-A1 CLASS OF ALKYLPHENOL COMPOUNDS AND PREPARATION METHOD THEREFOR Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) 2024-04-17 — — EP disclosed
WO-2007071348-A1 ISOQUINOLINE AMINOPYRAZOLE DERIVATIVES, THEIR MANUFACTURE AND USE AS PHARMACEUTICAL AGENTS FOR THE TREATMENT OF CANCER F. HOFFMANN-LA ROCHE AG (CH) 2007-06-28 — — WO disclosed
WO-2006111233-A1 ANTIOXIDANTS MERCK PATENT GMBH (DE) 2006-10-26 — — WO disclosed
WO-2006111234-A1 UV PROTECTION MERCK PATENT GMBH (DE) 2006-10-26 — — WO disclosed
WO-2004011446-A1 INDANE, DIHYDROBENZOFURAN, AND TETRAHYDRONAPHTHALENE CARBOXYLIC ACID DERIVATIVES AND THEIR USE AS ANTIDIABETICS BAYER PHARMACEUTICALS CORPORATION (US) 2004-02-05 — — WO disclosed
US-6459001-B1 Tricyclic compounds, their preparation process and the intermediates of this process, their use as medicaments and the pharmaceutical compositions containing them AVENTIS PHARMA S.A. (FR) 2002-10-01 — — US disclosed
US-6221907-B1 Tricyclic compounds having activity specific for integrins, particularly alphanubeta3 integrins, method for preparing same, intermediates therefor, use of said compounds as drugs, and pharmaceutical compositions containing same HOECHST MARION ROUSSEL (FR) 2001-04-24 — — US disclosed
WO-1995011880-A1 SUBSTITUTED AMIDES AS TACHYKININ ANTAGONISTS MERCK SHARP & DOHME LIMITED (GB) 1995-05-04 — — WO disclosed
US-5066658-A Enzyme Inhibitors; Bronchodilators; Antiinflammatory Agents ORTHO PHARMACEUTICAL CORPORATION (US) 1991-11-19 — — US disclosed
US-3962282-A JUVENILE HORMONE MIMICS ELI LILLY AND COMPANY (US) 1976-06-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260062393-A1 Compounds SCN2B, ABCB11, SCN1B FFAR1 1079/4885POLB 4118/4885AKR1B1 1433/4885
US-20240351966-A1 CLASS OF ALKYLPHENOL COMPOUNDS AND PREPARATION METHOD THEREFOR CYP4A11, CYP27A1, CYP4F11 FFAR1 29/4885POLB 2266/4885AKR1B1 104/4885
US-12365655-B2 Compounds SLC10A1, ABCB11, PCSK9 FFAR1 3711/4885POLB 3604/4885AKR1B1 630/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.