Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 4/20 | 0.52 |
| ▸ | TP53 | P04637 | 4/20 | 0.52 |
| ▸ | CETP | P11597 | 8/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | RGS12 | O14924 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10674706 | 0.81 | MDM4 (0.50) | MDM4TP53CETPMDM2TDP1 | |
| SCHEMBL2204567 | 0.77 | GABRA1 (0.43) | TP53TDP1IDO1CYP3A4ALOX15 | |
| SCHEMBL26385190 | 0.77 | NPC1 (0.48) | TDP1MAPT | |
| SCHEMBL2230553 | 0.77 | NPC1 (0.48) | TDP1MAPT | |
| SCHEMBL9297138 | 0.76 | MAPT (0.43) | TP53TDP1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL15742977 | 0.76 | KMT2A (0.49) | CYP3A4CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL28191118 | 0.76 | L3MBTL1 (0.44) | TP53ADRA1AADRA2CMEN1KMT2A | |
| SCHEMBL11520827 | 0.76 | KCNQ2 (0.44) | CYP2C19MEN1KMT2AMAPT | |
| SCHEMBL31753773 | 0.75 | ALDH1A1 (0.50) | TDP1TSHRMEN1KMT2AMAPT | |
| SCHEMBL143227 | 0.74 | ALDH1A1 (0.34) | MDM4TP53TDP1IDO1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115990277-A | Silica-based fluorescent nanoparticles | 斯隆-凯特林癌症研究院 | 2023-04-21 | — | — | CN | disclosed |