SCHEMBL143227

SCHEMBL143227

Cc1c(NC(C)O)cccc1NC(C)O

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.34
MAPT P10636 4/20 0.34
LMNA P02545 4/20 0.34
HTT P42858 2/20 0.34
CYP2C9 P11712 2/20 0.34
PKM P14618 1/20 0.34
GLA P06280 1/20 0.33
KDM4E B2RXH2 1/20 0.33
KEAP1 Q14145 1/20 0.32
NFE2L2 Q16236 1/20 0.32
CYP1A2 P05177 2/20 0.32
CYP3A4 P08684 2/20 0.32
PTGS1 P23219 2/20 0.32
HIF1A Q16665 2/20 0.32
MEN1 O00255 1/20 0.32
AKR1B10 O60218 1/20 0.32
TRPA1 O75762 1/20 0.32
ABCB11 O95342 1/20 0.32
DHFR P00374 1/20 0.32
MPO P05164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11454361 0.89 MAPT (0.46) ALDH1A1MAPTLMNAHTTCYP2C9
SCHEMBL3879398 0.87 TRPA1 (0.45) ALDH1A1MAPTLMNAHTTKDM4E
SCHEMBL25914650 0.86 ALDH1A1 (0.46) ALDH1A1LMNAPKMMEN1KMT2A
SCHEMBL21748421 0.82 ALDH1A1 (0.36) ALDH1A1MAPTLMNAHTTCYP2C9
SCHEMBL11806943 0.80 TDP1 (0.44) ALDH1A1MAPTLMNAHTTPKM
SCHEMBL2230553 0.79 NPC1 (0.48) ALDH1A1MAPTLMNAHTTKDM4E
SCHEMBL26385190 0.79 NPC1 (0.48) ALDH1A1MAPTLMNAHTTKDM4E
SCHEMBL4050170 0.79 ALDH1A1 (0.50) ALDH1A1MAPTLMNAHTTCYP2C9
SCHEMBL23095952 0.78 FFAR4 (0.52) ALDH1A1MAPTLMNAGLAKDM4E
SCHEMBL20171110 0.77 CYP1A2 (0.50) ALDH1A1HTTCYP2C9GLACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 398 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144724-A1 Mixture of at least five surfactants (I1) to (I5) WELLA GERMANY GMBH (DE) 2026-05-28 US claimed
US-12636241-B1 Method and composition for oxidative hair coloring WELLA OPERATIONS US LLC (US) 2026-05-26 US claimed
EP-4552630-A1 RESORCINOL FREE PERMANENT HAIR COLOR COMPOSITION AND METHOD Wella Operations US, LLC (US) 2025-05-14 EP claimed
CN-117801249-A Glass fiber/carbon fiber dispersion compatilizer, preparation method and application thereof 威海晨源分子新材料有限公司 2024-04-02 CN claimed
CN-116440026-A Preparation process of hair dye with low irritation and color protection function 佛山市喜妆化妆品有限公司 2023-07-18 CN claimed
CN-115919663-A Hair dyeing essential oil and preparation method thereof 广州市芊彩化妆品有限公司 2023-04-07 CN claimed
CN-115429717-A Fog blue gray hair dyeing cream 广州红鑫龙化妆品有限公司 2022-12-06 CN claimed
CN-114425027-A Hair dye and preparation method thereof 广州市芊彩化妆品有限公司 2022-05-03 CN claimed
CN-112955112-A Two-component system for artificial hair coloring 汉高股份有限及两合公司 2021-06-11 CN claimed
CN-112625776-A Graphene compound for lubricating oil additive and preparation method and application thereof 中国石油化工股份有限公司 2021-04-09 CN claimed
US-6736860-B2 ESPECIALLY STEARYL ALCOHOL, CETEARETH-20, CETYL ALCOHOL AND MIXTURES THEREOF. UNILEVER HOME & PERSONAL CARE USA DIVISION OF CONOPCO, INC. 2004-05-18 US claimed
US-6736861-B2 HAIR COLORING HAVING A SET TIME INTERVAL BETWEEN TWO CONSECUTIVE TREATMENTS, REPEAT THE SAME CONSECUTIVE TREATMENTS ABOUT 2 TO 30 TIMES UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2004-05-18 US claimed
US-20040083557-A1 Permanent coloring of hair using carbonate salts and bicarbonate salts and using percarbamic acid precursors UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2004-05-06 US claimed
US-6726729-B2 DYEING USING MIXTURES OF OXIDATION COLOR DYE CHEMICAL INTERMEDIATES, HAIR CONDITIONERS AND OXIDIZERS IN SHAMPOOS, THEN RINSING WITH WATER UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2004-04-27 US claimed
US-6709468-B2 HAVING TWO ALIPHATIC CHAINS OF 12 TO 18 CARBONS AND HAVING TWO IDENTICAL OR DIFFERENT SHORT CHAIN ALKYL GROUPS OF ONE OR TWO CARBONS; CONDITIONER; OXIDATION HAIR DYES UNILEVER HOME & PERSONAL CARE USA 2004-03-23 US claimed
US-20030172468-A1 Gradual permanent coloring of hair using dye intermediates dissolved in alkaline water with a gelling agent UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2003-09-18 US claimed
US-20030154561-A1 Gradual permanent coloring of hair using dye intermediates in a shampoo base UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2003-08-21 US claimed
US-20030154562-A1 Two step permanent coloring of hair UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2003-08-21 US claimed
US-20030140428-A1 Gradual permanent coloring of hair using dye intermediates in a shampoo base UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2003-07-31 US claimed
US-20030074748-A1 Method and composition for the gradual permanent coloring of hair UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2003-04-24 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12636241-B1 Method and composition for oxidative hair coloring POLB, DAO, ALPP ALDH1A1 200/4885MAPT 2639/4885LMNA 1280/4885
US-20260144724-A1 Mixture of at least five surfactants (I1) to (I5) DEGS1, SGMS1, FABP4 ALDH1A1 3076/4885MAPT 3250/4885LMNA 3521/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.